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慢性单侧上运动神经元病变所致步态障碍的管理:综述。

Management of Gait Impairments in Chronic Unilateral Upper Motor Neuron Lesions: A Review.

机构信息

Department of Rehabilitation, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, Nijmegen, the Netherlands.

Department of Rehabilitation, Sint Maartenskliniek, Nijmegen, the Netherlands.

出版信息

JAMA Neurol. 2018 Jun 1;75(6):751-758. doi: 10.1001/jamaneurol.2017.5041.

Abstract

IMPORTANCE

Gait impairments are common in patients with chronic supratentorial upper motor neuron lesions and are a source of disability. Clinical management aimed at improving the gait pattern in these patients is generally perceived as a challenging task because many possible abnormalities may interact. Moreover, a multitude of treatment options exist, ranging from assistive devices and muscle stretching to pharmacologic and surgical interventions, but evidence is inconclusive for most approaches and clear treatment guidelines are lacking.

OBSERVATIONS

Gait deviations in adults with a chronic supratentorial upper motor neuron lesion can approximately be reduced to the following 3 groups of primary deficits: (1) imbalance of muscle strength, length, and activity around the ankle and tarsal joints leading to pes equinovarus or pes equinus; (2) calf muscle weakness; and (3) overactivity of proximal leg muscles.

CONCLUSIONS AND RELEVANCE

A stepwise treatment algorithm emphasizes medical-technical interventions, which are based on evidence when available and otherwise reflect practice-based experience.

摘要

重要性

步态障碍在慢性幕上运动神经元损伤患者中很常见,是导致残疾的一个原因。临床管理旨在改善这些患者的步态模式,但通常被认为是一项具有挑战性的任务,因为可能存在许多相互作用的异常情况。此外,存在多种治疗选择,从辅助设备和肌肉拉伸到药物和手术干预,但大多数方法的证据并不明确,缺乏明确的治疗指南。

观察结果

成人慢性幕上运动神经元损伤的步态偏差大致可归结为以下 3 组主要缺陷:(1)踝关节和跗骨关节周围肌肉力量、长度和活动的不平衡,导致马蹄内翻或马蹄足;(2)小腿肌肉无力;(3)小腿近端肌肉过度活跃。

结论和相关性

逐步治疗算法强调基于现有证据的医疗技术干预,否则则反映基于实践经验的干预。

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