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广泛的脉络膜上腔出血后小梁切除术与丝裂霉素 C。

Extensive Submacular Hemorrhage After Trabeculectomy With Mitomycin C.

机构信息

Department of Ophthalmology, School of Medicine, Gyeongsang National University Hospital.

Institute of Health Science, Gyeongsang National University, Jinju.

出版信息

J Glaucoma. 2018 May;27(5):e92-e94. doi: 10.1097/IJG.0000000000000923.

Abstract

PURPOSE

We report the occurrence of an extensive submacular hemorrhage after trabeculectomy with mitomycin C in a patient with an occult choroidal neovascular membrane (CNVM).

PATIENTS AND METHODS

A 66-year-old man had a 3-year history of primary open-angle glaucoma in the left eye, which had been treated with topical antiglaucoma medication. The patient had age-related macular degeneration with an occult CNVM, for which he had received 5 intravitreal injections of ranibizumab and 5 intravitreal injections of bevacizumab in the left eye over a 3-year period. As intraocular pressure was not under control in the left eye over a 2-month period, trabeculectomy with mitomycin C was performed.

RESULTS

On the first postoperative day, intraocular pressure was 8 mm Hg with a well-formed bleb in the left eye. However, extensive subretinal hemorrhage was observed, and the patient underwent pneumatic displacement and pars plana vitrectomy to remove the hemorrhage. After 7 months, extensive subretinal fibrosis was observed and visual acuity was low (hand movement only).

CONCLUSIONS

To our knowledge, this is the first report of an extensive submacular hemorrhage after trabeculectomy with mitomycin C in a patient with an occult CNVM.

摘要

目的

我们报告了一例在伴有丝裂霉素 C 的小梁切除术后发生广泛的黄斑下出血的病例,该患者患有隐匿性脉络膜新生血管膜(CNVM)。

患者和方法

一名 66 岁男性左眼患有原发性开角型青光眼 3 年,曾接受局部抗青光眼药物治疗。该患者患有年龄相关性黄斑变性伴隐匿性 CNVM,为此他在左眼接受了 5 次雷珠单抗玻璃体腔内注射和 5 次贝伐单抗玻璃体腔内注射治疗。由于左眼眼压在 2 个月内未得到控制,因此进行了伴有丝裂霉素 C 的小梁切除术。

结果

左眼术后第 1 天,眼压为 8mmHg,形成了良好的滤过泡。然而,观察到广泛的视网膜下出血,患者接受了气动移位和经睫状体平坦部玻璃体切除术以清除出血。7 个月后,观察到广泛的视网膜下纤维化,视力低下(仅手动)。

结论

据我们所知,这是首例在伴有隐匿性 CNVM 的患者中发生伴有丝裂霉素 C 的小梁切除术后广泛黄斑下出血的报告。

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