Department of Ophthalmology, School of Medicine, Gyeongsang National University Hospital.
Institute of Health Science, Gyeongsang National University, Jinju.
J Glaucoma. 2018 May;27(5):e92-e94. doi: 10.1097/IJG.0000000000000923.
We report the occurrence of an extensive submacular hemorrhage after trabeculectomy with mitomycin C in a patient with an occult choroidal neovascular membrane (CNVM).
A 66-year-old man had a 3-year history of primary open-angle glaucoma in the left eye, which had been treated with topical antiglaucoma medication. The patient had age-related macular degeneration with an occult CNVM, for which he had received 5 intravitreal injections of ranibizumab and 5 intravitreal injections of bevacizumab in the left eye over a 3-year period. As intraocular pressure was not under control in the left eye over a 2-month period, trabeculectomy with mitomycin C was performed.
On the first postoperative day, intraocular pressure was 8 mm Hg with a well-formed bleb in the left eye. However, extensive subretinal hemorrhage was observed, and the patient underwent pneumatic displacement and pars plana vitrectomy to remove the hemorrhage. After 7 months, extensive subretinal fibrosis was observed and visual acuity was low (hand movement only).
To our knowledge, this is the first report of an extensive submacular hemorrhage after trabeculectomy with mitomycin C in a patient with an occult CNVM.
我们报告了一例在伴有丝裂霉素 C 的小梁切除术后发生广泛的黄斑下出血的病例,该患者患有隐匿性脉络膜新生血管膜(CNVM)。
一名 66 岁男性左眼患有原发性开角型青光眼 3 年,曾接受局部抗青光眼药物治疗。该患者患有年龄相关性黄斑变性伴隐匿性 CNVM,为此他在左眼接受了 5 次雷珠单抗玻璃体腔内注射和 5 次贝伐单抗玻璃体腔内注射治疗。由于左眼眼压在 2 个月内未得到控制,因此进行了伴有丝裂霉素 C 的小梁切除术。
左眼术后第 1 天,眼压为 8mmHg,形成了良好的滤过泡。然而,观察到广泛的视网膜下出血,患者接受了气动移位和经睫状体平坦部玻璃体切除术以清除出血。7 个月后,观察到广泛的视网膜下纤维化,视力低下(仅手动)。
据我们所知,这是首例在伴有隐匿性 CNVM 的患者中发生伴有丝裂霉素 C 的小梁切除术后广泛黄斑下出血的报告。