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输卵管咽瘘作为七匹马喉囊真菌病的一种治疗方法。

Salpingopharyngeal fistula as a treatment for guttural pouch mycosis in seven horses.

作者信息

Watkins A R, Parente E J

机构信息

University of Pennsylvania New Bolton Center, Kennett Square, Pennsylvania, USA.

出版信息

Equine Vet J. 2018 Nov;50(6):781-786. doi: 10.1111/evj.12830. Epub 2018 Apr 24.

Abstract

BACKGROUND

Guttural pouch mycosis (GPM) is a cause of nasal discharge, dysphagia and fatal haemorrhage in the horse.

OBJECTIVES

To report the complications and success of salpingopharyngeal fistulation in horses with GPM. We hypothesised that creating a direct static opening into the guttural pouch from the pharynx would cause a regression of fungal plaques due to a change in the guttural pouch environment and that this treatment would result in resolution of infection prior to secondary complications.

STUDY DESIGN

Retrospective case series.

METHODS

The medical records of all horses diagnosed with GPM that were presented to New Bolton Center between the years 2006 and 2017 were examined retrospectively. Seven cases of guttural pouch mycosis treated with salpingopharyngostomy without other surgical intervention were included. Information collected included signalment, presenting complaint, which pouch was affected, size and location of the plaques, laryngeal and pharyngeal function, concurrent medical therapy, location of the fistula, surgical time, time to resolution of clinical signs, time to full resolution of the mycotic plaque, and patency of the salpingopharyngostomy site.

RESULTS

Nasal discharge resolved in 10-30 days post-operatively in all cases where nasal discharge was present. The mycotic plaques showed complete resolution at time points ranging from 1 to 6 months post-operatively. No case developed epistaxis or neurological deficits post-operatively that were not present at presentation.

MAIN LIMITATIONS

There were differing adjunctive treatments between cases. This technique is not appropriate for horses that have had epistaxis or are currently bleeding.

CONCLUSIONS

Salpingopharyngostomy can minimise cost of treatment, be performed on an outpatient basis and provide better exposure of the infected area with few complications. This case series documents seven cases treated with this method that resolved the infection without any further complications of the mycosis.

摘要

背景

咽鼓管囊肿霉菌病(GPM)是马出现鼻液、吞咽困难和致命性出血的一个病因。

目的

报告患有GPM的马进行咽鼓管咽造瘘术的并发症及成功率。我们假设通过从咽部直接向咽鼓管囊肿创建一个静态开口,会因咽鼓管囊肿环境的改变而导致真菌斑消退,并且这种治疗会在继发并发症之前使感染得到解决。

研究设计

回顾性病例系列研究。

方法

对2006年至2017年间送至新博尔顿中心诊断为GPM的所有马匹的病历进行回顾性检查。纳入7例接受咽鼓管咽造口术且未进行其他手术干预治疗咽鼓管囊肿霉菌病的病例。收集的信息包括动物特征、就诊主诉、受影响的囊肿、菌斑的大小和位置、喉和咽功能、同时进行的药物治疗、瘘管位置、手术时间、临床症状消退时间、真菌斑完全消退时间以及咽鼓管咽造口术部位的通畅情况。

结果

在所有有鼻液的病例中,术后10 - 30天鼻液消失。真菌斑在术后1至6个月的时间点完全消退。术后没有病例出现鼻出血或神经功能缺损,这些症状在就诊时也不存在。

主要局限性

病例之间的辅助治疗有所不同。该技术不适用于有鼻出血或正在出血的马匹。

结论

咽鼓管咽造口术可以降低治疗成本,可在门诊进行,并能更好地暴露感染区域,并发症较少。本病例系列记录了7例采用该方法治疗的病例,感染得到解决且没有霉菌病的任何进一步并发症。

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