Kang Min-Kyung, Joung Boyoung, Shim Chi Young, Cho In Jeong, Yang Woo-In, Moon Jeonggeun, Jang Yangsoo, Chung Namsik, Chang Byung-Chul, Ha Jong-Won
Division of Cardiology, Kangnam Sacred Heart Hospital, Hallym University Medical Center, Seoul, South Korea.
Division of Cardiology and Cardiovascular Surgery, Severance Cardiovascular Hospital, Yonsei University College of Medicine, 134 Shinchon-dong, Seodaemun-gu, Seoul, 120-752, Republic of Korea.
Cardiovasc Ultrasound. 2018 Mar 9;16(1):5. doi: 10.1186/s12947-018-0123-1.
Atrial fibrillation (AF) can occur even after the correction of mitral valve (MV) pathology in patients who have pre-operative sinus rhythm and undergo MV surgery. However, the factors associated with the occurrence of AF after MV surgery are still unclear. The aim of this retrospective study was to investigate the factors determining the occurrence of permanent AF after MV surgery in patients with preoperative sinus rhythm who underwent MV surgery.
Four hundred and forty-two patients (mean age 46 ± 12, 190 men) who underwent MV surgery and sinus rhythm were investigated retrospectively. Transthoracic echocardiography was performed before and after MV surgery at the time of dismissal.
Permanent post-operative AF occurred in 81 (18%) patients even after successful MV surgery and preoperative sinus rhythm. It was more common in rheumatic etiology, a presence of mitral stenosis, lower pre- and post-operative left ventricular ejection fraction, higher post-operative mean diastolic pressure gradient across mitral prosthesis, larger post-operative left atrial volume index (LAVI) and lesser degrees of reduction in LAVI after surgery. In multiple regression analysis, post-operative LAVI was found to be an independent predictor for occurrence of AF. Post-operative LAVI > 39 ml/m2 was the cut-off value for best prediction of new onset permanent AF (sensitivity: 79%, AUC: 0.762, SE: 0.051, p < 0.001).
New-onset permanent post-operative AF is not uncommon, even after successful MV surgery despite pre-operative sinus rhythm. Larger post-operative LAVI was an independent predictor for the occurrence of AF.
对于术前为窦性心律并接受二尖瓣手术的患者,即使在二尖瓣病变得到纠正后仍可能发生心房颤动(房颤)。然而,二尖瓣手术后房颤发生的相关因素仍不明确。这项回顾性研究的目的是调查在接受二尖瓣手术且术前为窦性心律的患者中,决定二尖瓣手术后永久性房颤发生的因素。
对442例接受二尖瓣手术且为窦性心律的患者(平均年龄46±12岁,男性190例)进行回顾性研究。在出院时对二尖瓣手术前后进行经胸超声心动图检查。
即使二尖瓣手术成功且术前为窦性心律,仍有81例(18%)患者术后发生永久性房颤。在风湿性病因、存在二尖瓣狭窄、术前和术后左心室射血分数较低、术后二尖瓣人工瓣膜平均舒张压梯度较高、术后左心房容积指数(LAVI)较大以及术后LAVI降低程度较小的患者中更常见。在多元回归分析中,发现术后LAVI是房颤发生的独立预测因素。术后LAVI>39 ml/m²是预测新发永久性房颤的最佳截断值(敏感性:79%,AUC:0.762,SE:0.051,p<0.001)。
即使二尖瓣手术成功且术前为窦性心律,术后新发永久性房颤也并不少见。术后较大的LAVI是房颤发生的独立预测因素。