Jeon Ikchan, Cho Yong Eun
Department of Neurosurgery, Yeungnam University Hospital, Yeungnam University College of Medicine, Daegu, Korea.
Department of Neurosurgery, Gangnam Severance Hospital, The Spinal and Spinal Cord Institute, Yonsei University College of Medicine, Seoul, Korea.
J Korean Neurosurg Soc. 2018 Mar;61(2):224-232. doi: 10.3340/jkns.2017.1201.003. Epub 2018 Feb 28.
Cervical ossification of the posterior longitudinal ligament (OPLL) can be treated via anterior or posterior approach, or both. The optimal approach depends on the characteristics of OPLL and cervical curvature. Although most patients can be successfully treated by a single surgery with the proper approach, renewed or newly developed neurological deterioration often requires repeat surgery.
Twenty-seven patients with renewed or newly developed neurological deterioration requiring salvage surgery for multi-segment cervical OPLL were enrolled. Ten patients (group AP) underwent anterior approach, and 17 patients (group PA) underwent posterior approach at the initial surgery. Clinical and radiological data from initial and repeat surgeries were obtained and analyzed retrospectively.
The intervals between the initial and repeat surgeries were 102.80±60.08 months (group AP) and 61.00±8.16 months (group PA) (<0.05). In group AP, the main OPLL lesions were removed during the initial surgery. There was a tendency that the site of main OPLL lesions causing renewed or newly developed neurological deterioration were different from that of the initial surgery (8/10, <0.05). Repeat surgery was performed for progressed OPLL lesions at another segment as the main pathology. In group PA, the main OPLL lesions at the initial surgery continued as the main pathology for repeat surgery. Progression of kyphosis in the cervical curvature (Cobb's angle on C2-7 and segmental angle on the main OPLL lesion) was noted between the initial and repeat surgeries. Group PA showed more kyphotic cervical curvature compared to group AP at the time of repeat surgery (<0.05).
The reasons for repeat surgery depend on the type of initial surgery. The main factors leading to repeat surgery are progression of remnant OPLL at a different segment in group AP and kyphotic change of the cervical curvature in group PA.
颈椎后纵韧带骨化症(OPLL)可通过前路或后路手术治疗,也可两者联合。最佳手术方式取决于OPLL的特征和颈椎曲度。尽管大多数患者通过合适的手术方式单次手术即可成功治疗,但再次出现或新发生的神经功能恶化往往需要再次手术。
纳入27例因多节段颈椎OPLL出现再次或新发生神经功能恶化而需要挽救手术的患者。10例患者(AP组)初次手术采用前路手术,17例患者(PA组)初次手术采用后路手术。回顾性收集并分析初次手术和再次手术的临床及影像学资料。
初次手术与再次手术的间隔时间在AP组为102.80±60.08个月,在PA组为61.00±8.16个月(<0.05)。AP组在初次手术时已切除主要的OPLL病变。导致再次或新发生神经功能恶化的主要OPLL病变部位与初次手术时不同,存在这种趋势(8/10,<0.05)。再次手术时以另一节段进展的OPLL病变作为主要病理进行处理。PA组初次手术时的主要OPLL病变在再次手术时仍为主要病理。初次手术与再次手术之间,颈椎曲度后凸加重(C2-7 Cobb角及主要OPLL病变节段角)。再次手术时,PA组颈椎后凸曲度比AP组更明显(<0.05)。
再次手术的原因取决于初次手术的类型。导致再次手术的主要因素在AP组是不同节段残留OPLL的进展,在PA组是颈椎曲度的后凸改变。