From R1 Engineering, Euclid, Ohio.
Department of Biomedical Engineering, Lerner Research Institute (LRI), Cleveland Clinic, Cleveland, Ohio.
ASAIO J. 2019 Jan;65(1):e1-e3. doi: 10.1097/MAT.0000000000000772.
Control of mechanical circulatory support pump output typically requires that pressure-regulating functions be accomplished by active control of the speed or geometry of the device, with feedback from pressure or flow sensors. This article presents a different design approach, with a pressure-regulating device as the core design feature, allowing the essential control function of regulating pressure to be directly programmed into the hydromechanical design. We show the step-by-step transformation of a pressure-regulating device into a continuous-flow total artificial heart that passively balances left and right circulations without the need for pressure and flow sensors. In addition, we discuss a ventricular assist device that prevents backflow in the event of power interruption and also dynamically interacts with residual ventricle function to preserve pulsatility.
机械循环支持泵输出的控制通常需要通过设备速度或几何形状的主动控制以及压力或流量传感器的反馈来实现压力调节功能。本文提出了一种不同的设计方法,以压力调节装置为核心设计特点,允许将调节压力的基本控制功能直接编程到流体力学设计中。我们展示了如何将压力调节装置逐步转化为连续流全人工心脏,无需压力和流量传感器即可被动平衡左右循环。此外,我们还讨论了一种心室辅助装置,该装置在电源中断时防止回流,并与残余心室功能动态相互作用以保持脉动。