Heese Sandra, Hammer Kerstin, Möllers Mareike, Köster Helen A, Falkenberg Maria K, Eveslage Maria, Braun Janina, Oelmeier de Murcia Kathrin, Klockenbusch Walter, Schmitz Ralf
Department of Obstetrics and Gynecology, University Hospital of Münster, Münster, Germany.
Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany.
J Perinat Med. 2018 Oct 25;46(8):900-904. doi: 10.1515/jpm-2017-0339.
Objective To compare the adrenal gland size of fetal growth restricted (FGR) and normal control fetuses. Study design In this prospective study the adrenal gland size of 63 FGR fetuses and 343 normal controls was measured between 20 and 41 weeks of gestation. The total width and the medulla width were measured in a new standardized transversal plane. The cortex width and a calculated ratio of the total and medulla width (adrenal gland ratio) were compared between both groups. Results The mean cortex width and the adrenal gland ratio in FGR fetuses were higher in comparison to the controls (P<0.001; P=0.036, respectively). The cortex width correlated positively with the gestational age (control group: P<0.001; FGR group: P=0.089) whilst the adrenal gland ratio showed no association with the gestational age (control group: P=0.153; FGR group: P=0.314). Conclusion The adrenal gland cortex width and the adrenal gland ratio were increased in FGR fetuses compared to normal fetuses.
目的 比较胎儿生长受限(FGR)胎儿与正常对照胎儿的肾上腺大小。研究设计 在这项前瞻性研究中,对63例FGR胎儿和343例正常对照胎儿在妊娠20至41周期间的肾上腺大小进行了测量。在一个新的标准化横断面上测量总宽度和髓质宽度。比较两组之间的皮质宽度以及计算得出的总宽度与髓质宽度之比(肾上腺比率)。结果 与对照组相比,FGR胎儿的平均皮质宽度和肾上腺比率更高(分别为P<0.001;P=0.036)。皮质宽度与胎龄呈正相关(对照组:P<0.001;FGR组:P=0.089),而肾上腺比率与胎龄无关联(对照组:P=0.153;FGR组:P=0.314)。结论 与正常胎儿相比,FGR胎儿的肾上腺皮质宽度和肾上腺比率增加。