Zenunaj Gladiol, Spataro Claudio, Traina Luca, Gasbarro Vincenzo
Unit of Vascular and Endovascular Surgery, University Hospital of Ferrara, Italy.
Int J Surg Case Rep. 2017 Nov 12;41:411-413. doi: 10.1016/j.ijscr.2017.11.010. eCollection 2017.
Biosynthetic prosthesis has become the trend to carry out arterial reconstruction in infected sites since considered to be resistant to infection. Late graft occlusion is the only complication reported in literature so far. We report a case of biosynthetic graft infection which led to early detachment of the femoral anastomosis of a femoral-popliteal above-knee bypass.
A 76-year-old man developed groin infection 3 months later after performing an ePTFE femoral-popliteal above-knee bypass for critical limb ischemia. He was re-admitted for groin infection involving the vascular structures. Explantation of the existing bypass and its replacement with a biosynthetic graft (omniflow II) was performed. Detachment of the proximal anastomosis occurred 6 days later leading to groin haematoma. Consequently, retroperitoneal access was performed for clamping the external iliac artery so as to control haemorrhage followed by explantation of the biosynthetic graft. An external iliac-popliteal above-knee bypass was tailored in order to save the limb and it was performed using a transobturator approach avoiding the infected site. In both cases bacterial cultures resulted positive for Morganella Morganii. The groin wound was treated separately with negative pressure medication healing definitively within 20 days and after 3-month follow-up the bypass was still patent.
This is the first report of biosynthetic graft infection used for infrainguinal reconstruction leading to haemorrhage due to anastomosis disrupture. Using an extra-anatomical access for providing blood inflow to the leg avoiding the infected site and treating safely the groin wound with VAC therapy revealed to be a valid approach.
生物合成假体被认为具有抗感染能力,已成为在感染部位进行动脉重建的趋势。晚期移植物闭塞是迄今为止文献中报道的唯一并发症。我们报告一例生物合成移植物感染病例,该感染导致股腘动脉膝上旁路移植术的股部吻合口早期分离。
一名76岁男性在因严重肢体缺血行ePTFE股腘动脉膝上旁路移植术后3个月出现腹股沟感染。他因腹股沟感染累及血管结构再次入院。取出现有的旁路移植并更换为生物合成移植物(omniflow II)。6天后近端吻合口分离,导致腹股沟血肿。因此,经腹膜后途径夹闭髂外动脉以控制出血,随后取出生物合成移植物。为挽救肢体定制了髂外动脉-腘动脉膝上旁路移植术,并采用经闭孔途径进行,避开感染部位。在这两例中,细菌培养结果显示摩根氏摩根菌呈阳性。腹股沟伤口单独进行负压治疗,20天内完全愈合,3个月随访后旁路移植仍通畅。
这是首例关于用于腹股沟下重建的生物合成移植物感染导致吻合口破裂出血的报告。采用解剖外途径为腿部提供血流,避开感染部位,并通过负压封闭引流疗法安全治疗腹股沟伤口,这被证明是一种有效的方法。