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法医精神病学中精神障碍的抗精神病药物治疗:患者对强制治疗的认知及其预测因素。

Antipsychotic treatment of psychotic disorders in forensic psychiatry: Patients' perception of coercion and its predictors.

作者信息

Horvath Juliane, Steinert Tilman, Jaeger Susanne

机构信息

Zentrum für Psychiatrie Südwürttemberg, Klinik für Psychiatrie und Psychotherapie Weissenau, Weingartshofer Straße 2, 88214 Ravensburg, Germany.

Zentrum für Psychiatrie Südwürttemberg, Klinik für Psychiatrie und Psychotherapie Weissenau, Weingartshofer Straße 2, 88214 Ravensburg, Germany.

出版信息

Int J Law Psychiatry. 2018 Mar-Apr;57:113-121. doi: 10.1016/j.ijlp.2018.02.004. Epub 2018 Mar 2.

Abstract

BACKGROUND

Despite the major encroachment of coercive measures on the fundamental rights of affected forensic psychiatric patients, there is relatively few research done in this field. Considering the relevance of this subject for psychiatric care and the recent changes of the legal basis of coercive treatment in Germany, more studies are needed. The present study examines forensic psychiatric inpatients' perception of coercion regarding the prescribed antipsychotic medication and factors associated with the perception of coercion.

MATERIAL AND METHODS

Patients with schizophrenia, schizotypal and delusional disorders in two forensic psychiatric institutions in Southern Germany were interviewed about their experience of coercion related to antipsychotic medication. Due to a lack of appropriate psychometric scales, the perception of coercion regarding antipsychotic medication was assessed using an adapted version of the MacArthur Admission Experience Survey (aAES). The influence of sociodemographic and illness-related factors, of the attitude towards medication, insight into illness and symptom severity on the extent to which patients felt coerced to take the prescribed medication was analyzed. Two Visual Analog Scales, the Drug Attitude Inventory DAI-10, the Positive and Negative Syndrome Scale PANSS, the Fragebogen zur Krankheitseinsicht (Questionnaire about insight into illness) FKE-10 and the Coercion Experience Scale CES were used as psychometric scales.

RESULTS

50% of all patients eligible for the study gave their written consent. 70% of all participants had experienced coercive measures between admission and time of data assessment. The DAI-10 and the aAES correlated moderately, a high level of insight into illness being correlated to less perceived coercion. The FKE-10 and the aAES correlated moderately as well, a high level of insight into illness being correlated to less perceived coercion. The severity of symptoms (PANSS score) and the level of perceived coercion (aAES score) correlated weakly, participants with more severe symptoms perceived more coercion than those with less marked symptoms. A linear regression model showed that to what extent patients felt coerced to take the prescribed antipsychotic medication was mainly influenced by their attitude towards medication and the degree of insight into illness, to a lesser extent by symptom severity (R = 0.565, p < 0.001). Sociodemographic factors were not related to the extent to which patients felt coerced to take the antipsychotic medication.

CONCLUSIONS

Predictors of the experience of coercion related to the prescribed antipsychotic medication of forensic psychiatric inpatients with schizophrenia and related disorders are not so much sociodemographic or illness-related factors as education or past medical history, but rather potentially influenceable variables such as insight into illness or attitude towards medication.

摘要

背景

尽管强制措施严重侵犯了受影响的法医精神病患者的基本权利,但该领域的研究相对较少。鉴于这一主题对精神科护理的相关性以及德国强制治疗法律依据的近期变化,需要更多的研究。本研究调查了法医精神病住院患者对规定的抗精神病药物强制治疗的看法以及与强制治疗看法相关的因素。

材料与方法

对德国南部两家法医精神病机构中患有精神分裂症、分裂型障碍和妄想性障碍的患者进行访谈,了解他们在抗精神病药物治疗方面的强制体验。由于缺乏合适的心理测量量表,使用麦克阿瑟入院体验调查问卷(aAES)的改编版评估患者对抗精神病药物治疗的强制感受。分析了社会人口统计学和疾病相关因素、对药物的态度、对疾病的洞察力以及症状严重程度对患者感到被迫服用规定药物程度的影响。使用了两个视觉模拟量表、药物态度量表DAI-10、阳性和阴性症状量表PANSS、疾病洞察力问卷FKE-10和强制体验量表CES作为心理测量量表。

结果

所有符合研究条件的患者中有50%给予了书面同意。所有参与者中有70%在入院至数据评估期间经历过强制措施。DAI-10与aAES呈中度相关,对疾病的高洞察力与较低的强制感受相关。FKE-10与aAES也呈中度相关,对疾病的高洞察力与较低的强制感受相关。症状严重程度(PANSS评分)与强制感受程度(aAES评分)呈弱相关,症状较严重的参与者比症状较轻的参与者感受到更多的强制。线性回归模型显示,患者感到被迫服用规定抗精神病药物的程度主要受其对药物的态度和对疾病的洞察程度影响,在较小程度上受症状严重程度影响(R = 0.565,p < 0.001)。社会人口统计学因素与患者感到被迫服用抗精神病药物的程度无关。

结论

对于患有精神分裂症及相关障碍的法医精神病住院患者,与规定的抗精神病药物强制治疗体验相关的预测因素与其说是社会人口统计学或疾病相关因素,如教育程度或既往病史,不如说是潜在可影响的变量,如对疾病的洞察力或对药物的态度。

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