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阴道和腹部盆腔器官脱垂修复术后1年女性的额外治疗、满意度、症状及生活质量

Additional treatments, satisfaction, symptoms and quality of life in women 1 year after vaginal and abdominal pelvic organ prolapse repair.

作者信息

Nguyen Laura N, Gruner Morgan, Killinger Kim A, Peters Kenneth M, Boura Judith A, Jankowski Michelle, Sirls Larry T

机构信息

Beaumont Health, 3535 W. 13 Mile Road, Room 428, Urology Administration, Royal Oak, MI, 48067, USA.

Oakland University William Beaumont School of Medicine, Royal Oak, MI, USA.

出版信息

Int Urol Nephrol. 2018 Jun;50(6):1031-1037. doi: 10.1007/s11255-018-1846-5. Epub 2018 Mar 16.

Abstract

OBJECTIVES

To evaluate additional treatments, symptoms, satisfaction and quality of life 1 year after vaginal and abdominal pelvic organ prolapse (POP) repair.

METHODS

Adult women enrolled in a prospective POP database were reviewed. Baseline and outcomes data 1 year after surgery were collected including the Pelvic Floor Distress Inventory (PFDI) and mailed surveys. Data were analyzed with descriptive statistics, Fisher's exact tests and t tests.

RESULTS

Of 222 women, 147 (66%) had vaginal and 75 (34%) had abdominal repair. Vaginal group patients were older (64.1 vs. 59.7 years; p = 0.003), but other demographic characteristics did not differ. Vaginal group patients had lower baseline anterior and apical prolapse grades (anterior 2.7 vs. 3.1, p = 0.003; apical 2.1 vs. 3.1, p < 0.001). Baseline PFDI scores were similar. Scores improved significantly for both groups after 1 year, but 1-year PFDI scores were significantly higher in the vaginal group (45.6 vs. 32.6, p = 0.032). Scores were not different when adjusted for age and prolapse grade (p = 0.24). At 1 year, most patients in the vaginal and abdominal groups reported moderately/markedly improved overall symptoms (72/108 vs. 50/60, p = 0.030) and quality of life (89/101 vs. 54/59, p = 0.601). Most were satisfied with surgery (68/101 vs. 48/59, p = 0.067). Retreatment rates (pelvic floor physical therapy, medications, coping strategies, surgical procedures) were similar (34/109 vs. 15/62, p = 0.381). Vaginal mesh use did not affect additional treatments, patient satisfaction or symptoms.

CONCLUSIONS

Although symptoms improve and most women are satisfied with surgery, about one in four women have additional therapy in the first year after POP repair.

摘要

目的

评估阴道和腹部盆腔器官脱垂(POP)修复术后1年的额外治疗、症状、满意度和生活质量。

方法

对纳入前瞻性POP数据库的成年女性进行回顾。收集手术1年后的基线和结局数据,包括盆底困扰量表(PFDI)和邮寄调查问卷。采用描述性统计、Fisher精确检验和t检验对数据进行分析。

结果

222名女性中,147名(66%)接受了阴道修复,75名(34%)接受了腹部修复。阴道修复组患者年龄较大(64.1岁对59.7岁;p = 0.003),但其他人口统计学特征无差异。阴道修复组患者基线时前壁和顶端脱垂分级较低(前壁2.7对3.1,p = 0.003;顶端2.1对3.1,p < 0.001)。基线PFDI评分相似。两组术后1年评分均显著改善,但阴道修复组1年PFDI评分显著更高(45.6对32.6,p = 0.032)。经年龄和脱垂分级调整后评分无差异(p = 0.24)。1年时,阴道修复组和腹部修复组的大多数患者报告总体症状有中度/显著改善(72/108对50/60,p = 0.030)和生活质量改善(89/101对54/59,p = 0.601)。大多数患者对手术满意(68/101对48/59,p = 0.067)。再治疗率(盆底物理治疗、药物、应对策略、手术操作)相似(34/109对15/62,p = 0.381)。使用阴道网片不影响额外治疗、患者满意度或症状。

结论

尽管症状有所改善且大多数女性对手术满意,但约四分之一的女性在POP修复术后第1年需要额外治疗。

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