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无缝合与传统主动脉瓣置换术:70例接受同期心脏手术的高危患者的结局

Sutureless versus Conventional Aortic Valve Replacement: Outcomes in 70 High-Risk Patients Undergoing Concomitant Cardiac Procedures.

作者信息

Hanedan Muhammet Onur, Yuruk Mehmet Ali, Parlar Ali Ihsan, Ziyrek Ugur, Arslan Ali Kemal, Sayar Ufuk, Mataraci Ilker

出版信息

Tex Heart Inst J. 2018 Feb 1;45(1):11-16. doi: 10.14503/THIJ-16-6092. eCollection 2018 Feb.

Abstract

In elderly, high-risk surgical patients, sutureless aortic valve replacement (AVR) can often be an alternative to conventional AVR; shorter aortic cross-clamp and cardiopulmonary bypass times are the chief advantages. We compared the outcomes of sutureless AVR with those of conventional AVR in 70 elderly patients who underwent concomitant cardiac surgical procedures. We retrospectively analyzed the cases of 42 men and 28 women (mean age, 70.4 ± 10.3 yr; range, 34-93 yr) who underwent cardiac operations plus AVR with either a sutureless valve (group 1, n=38) or a conventional bioprosthetic or mechanical valve (group 2, n=32). Baseline patient characteristics were similar except for worse New York Heart Association functional status and the prevalence of diabetes mellitus in group 1. In group 1, the operative, cross-clamp, and cardiopulmonary bypass times were shorter (all =0.001), postoperative drainage amounts were lower (=0.009), hospital stays were shorter (=0.004), and less red blood cell transfusion was needed (=0.037). Echocardiograms before patients' discharge from the hospital showed lower peak and mean aortic gradients in group 1 (mean transvalvular gradient, 8.4 ± 2.8 vs 12.2 ± 5.2 mmHg; =0.012). We found that elderly, high-risk patients who underwent multiple cardiac surgical procedures and sutureless AVR had better hemodynamic outcomes and shorter ischemic times than did patients who underwent conventional AVR.

摘要

在老年高危外科手术患者中,无缝合主动脉瓣置换术(AVR)通常可替代传统AVR;主动脉阻断和体外循环时间较短是其主要优势。我们比较了70例接受同期心脏手术的老年患者中无缝合AVR与传统AVR的结果。我们回顾性分析了42例男性和28例女性(平均年龄70.4±10.3岁;范围34 - 93岁)的病例,这些患者接受了心脏手术加AVR,其中一组使用无缝合瓣膜(第1组,n = 38),另一组使用传统生物假体或机械瓣膜(第2组,n = 32)。除第1组纽约心脏协会功能状态较差和糖尿病患病率较高外,两组患者的基线特征相似。在第1组中,手术、主动脉阻断和体外循环时间较短(均P = 0.001),术后引流量较少(P = 0.009),住院时间较短(P = 0.004),红细胞输注量较少(P = 0.037)。患者出院前的超声心动图显示第1组的主动脉峰值和平均梯度较低(平均跨瓣梯度,8.4±2.8 vs 12.2±5.2 mmHg;P = 0.012)。我们发现,接受多次心脏手术和无缝合AVR的老年高危患者比接受传统AVR的患者具有更好的血流动力学结果和更短的缺血时间。

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