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行为治疗联合丙戊酸治疗中风患者腭肌阵挛所致吞咽困难的有效性：两例报告

Effectiveness of Combining Behavioral Treatment With Valproic Acid for Dysphagia Caused by Palatal Myoclonus in Patients With Stroke: Two Case Reports.

作者信息

Kim Bo-Ram, Lee Yejin, Kim Soo Jin, Kim Hyuntae, Lee Jong Won, Lee Seunghwan, Lee Jongmin

机构信息

Department of Rehabilitation Medicine, Konkuk University School of Medicine & Konkuk University Medical Center, Seoul, Korea.

出版信息

Ann Rehabil Med. 2018 Feb;42(1):180-183. doi: 10.5535/arm.2018.42.1.180. Epub 2018 Feb 28.

DOI:10.5535/arm.2018.42.1.180
PMID:29560339
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5852223/
Abstract

Palatal myoclonus (PM) is a rare disease that may induce dysphagia. Since dysphagia related to PM is unique and is characterized by myoclonic movements of the involved muscles, specific treatments are needed for rehabilitation. However, no study has investigated the treatment effectiveness for this condition. Therefore, the aim of this case report was to describe the benefit of combining behavioral treatment with valproic acid administration in patients with dysphagia triggered by PM. The two cases were treated with combined treatment. The outcomes evaluated by videofluoroscopic swallowing studies before and after the treatment showed significant decreases in myoclonic movements and improved swallowing function. We conclude that the combined treatment was effective against dysphagia related to PM.

摘要

腭肌阵挛（PM）是一种可能导致吞咽困难的罕见疾病。由于与PM相关的吞咽困难具有独特性，其特征为受累肌肉的肌阵挛运动，因此康复需要特定的治疗方法。然而，尚无研究调查过针对这种情况的治疗效果。因此，本病例报告的目的是描述行为治疗与丙戊酸给药相结合对由PM引发吞咽困难患者的益处。这两个病例接受了联合治疗。治疗前后通过电视荧光吞咽造影检查评估的结果显示，肌阵挛运动显著减少，吞咽功能得到改善。我们得出结论，联合治疗对与PM相关的吞咽困难有效。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/5852223/84ea66b39f3f/arm-42-180-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/5852223/f05d862deac2/arm-42-180-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/5852223/84ea66b39f3f/arm-42-180-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/5852223/f05d862deac2/arm-42-180-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/34b6/5852223/84ea66b39f3f/arm-42-180-g002.jpg

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引用本文的文献

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Palato-pharyngo-laryngeal myoclonus with recurrent retrograde feeding tube migration after cerebellar hemorrhagic stroke: a case report and review of hypertrophic olivary degeneration.小脑脑出血后出现的腭咽喉肌阵挛伴反复逆行胃管迁移：病例报告并复习肥大性橄榄核变性。
BMC Neurol. 2020 Jun 3;20(1):222. doi: 10.1186/s12883-020-01800-6.

本文引用的文献

1
Palato-pharyngo-laryngeal myoclonus … an unusual cause of dysphagia.腭咽喉肌阵挛……一种不常见的吞咽困难病因。
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[Palatal myoclonus and dysphagia].[腭肌阵挛与吞咽困难]
Ann Readapt Med Phys. 2004 Feb;47(1):13-9. doi: 10.1016/j.annrmp.2003.07.002.
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Hypertrophic olivary degeneration following pontine haemorrhage: hypertensive crisis or cavernous haemangioma bleeding?桥脑出血后肥厚性橄榄体变性：高血压危象还是海绵状血管瘤出血？
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