躯干结节性囊性基底细胞癌：一名毫无戒心的年轻人面临的诊断难题。

Nodular Cystic Basal Cell Carcinoma of the Trunk: a Diagnostic Dilemma in an Unsuspecting Youth.

作者信息

Tyagi Ruchita, Kaur Dilpreet, Kaur Gursheen, Garg Bhavna, Sood Neena, Gupta Sunil

机构信息

Department of Pathology, Dayanand Medical College and Hospital, Ludhiana, India.

Department of Internal Medicine, Dayanand Medical College and Hospital, Ludhiana, India.

出版信息

Iran J Pathol. 2017 Fall;12(4):410-412. Epub 2017 Oct 1.

PMID:29563940

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5844689/

Abstract

Basal cell carcinoma (BCC) commonly affects the elderly and is mostly confined to the head and neck region. Only 10% of all cases occur on the trunk. We presented a case of bullous lesion on the abdomen in a young male, initially diagnosed by clinicians as a vascular nevus. Histopathological examination and immunohistochemistry (IHC) revealed it to be Nodular cystic variant of BCC. This rare variant of BCC morphologically resembles benign skin adnexal tumor of Eccrine syringofibroadenoma. Ber Ep4 positivity on IHC established the correct diagnosis. This case highlights that nodular cystic variant of BCC can be a diagnostic dilemma for clinicians and pathologists.

摘要

基底细胞癌（BCC）常见于老年人，大多局限于头颈部区域。所有病例中仅有10%发生于躯干。我们报告了1例年轻男性腹部的大疱性病变，临床医生最初诊断为血管痣。组织病理学检查和免疫组化（IHC）显示其为BCC的结节性囊性变体。这种罕见的BCC变体在形态上类似于良性皮肤附属器肿瘤小汗腺导管纤维腺瘤。免疫组化中Ber Ep4阳性确立了正确诊断。该病例强调BCC的结节性囊性变体可能给临床医生和病理学家带来诊断难题。