Park Do-Yang, Chung Hyo Jin, Park Sang Chul, Kim Jin Won, Yoon Joo-Heon, Lee Jeung-Gweon, Kim Chang-Hoon, Cho Hyung-Ju
Department of Otolaryngology, Ajou University School of Medicine, Suwon, Republic of Korea.
Department of Medicine, Yonsei University Graduate School, Seoul, Republic of Korea.
Eur Arch Otorhinolaryngol. 2018 May;275(5):1189-1196. doi: 10.1007/s00405-018-4940-5. Epub 2018 Mar 21.
Considerable number of patients with obstructive sleep apnea (OSA) failed to respond to positive airway pressure therapy and so turned to surgical procedures. A wide variety of surgical procedures have been developed and advanced, according to obstruction and target site through nasal cavity to trachea. We introduced our overlapping lateral pharyngoplasty (OLP) technique as a surgical option for OSA and evaluated its surgical outcomes both with and without endoscope-guided coblator tongue base resection (CobTBR).
Sixty-five patients underwent either OLP alone or OLP combined with CobTBR to treat OSA at academic tertiary center. Twenty-nine patients underwent postoperative polysomnography and were divided into two groups, as an OLP group and an OLP combined CobTBR group. Various parameters from physical examinations and polysomnographic results were compared and analyzed.
Most enrolled patients improved on various polysomnographic parameters, including AHI and oxygen levels. In the OLP group, 91.7% of patients showed a surgical response and the overall success rate was 66.7%. Mean AHI improved significantly from 36.3 to 14.8. In the OLP + CobTBR group, all patients showed improvement in AHI and the surgical response rate was 100%. The overall success rate was 70.6% and mean AHI improved from 38.8 to 13.1. In both groups, various parameters such as RDI, lowest O saturation, mean O saturation, oxygen desaturation index, supine AHI, and ESS significantly improved after surgery.
Our OLP technique appears to be safe and effective among OSA patients. Multi-level OLP surgery combined with CobTBR can be a good surgical strategy for patients experiencing retroglossal obstruction.
相当一部分阻塞性睡眠呼吸暂停(OSA)患者对气道正压通气治疗无反应,因此转而采用外科手术治疗。根据鼻腔至气管的阻塞部位和靶点,已开发并改进了多种外科手术方法。我们介绍了重叠外侧咽成形术(OLP)技术作为OSA的一种手术选择,并评估了其在有或没有内镜引导下舌根消融术(CobTBR)情况下的手术效果。
65例患者在学术三级中心接受单独的OLP或OLP联合CobTBR治疗OSA。29例患者术后接受多导睡眠图检查,并分为两组,即OLP组和OLP联合CobTBR组。对体格检查和多导睡眠图结果的各种参数进行比较和分析。
大多数入组患者在包括呼吸暂停低通气指数(AHI)和血氧水平在内的各种多导睡眠图参数上有所改善。在OLP组中,91.7%的患者显示出手术反应,总体成功率为66.7%。平均AHI从36.3显著改善至14.8。在OLP + CobTBR组中,所有患者的AHI均有改善,手术反应率为100%。总体成功率为70.6%,平均AHI从38.8改善至13.1。两组术后呼吸紊乱指数(RDI)、最低血氧饱和度、平均血氧饱和度、血氧饱和度下降指数、仰卧位AHI和爱泼沃斯思睡量表(ESS)等各种参数均显著改善。
我们的OLP技术在OSA患者中似乎是安全有效的。多级OLP手术联合CobTBR对于舌根后阻塞的患者可能是一种良好的手术策略。