López-Gómez Juan José, Izaola-Jáuregui Olatz, Torres-Torres Beatriz, Gómez-Hoyos Emilia, Castro Lozano María Ángeles, Ortolá-Buigues Ana, Martín Ferrero Miguel Ángel, De Luis-Román Daniel Antonio
Hospital Clínico Universitario Valladolid.
Nutr Hosp. 2018 Jan 16;35(1):71-77. doi: 10.20960/nh.1148.
Knee osteoarthritis is a disease with a high prevalence in our environment, especially in women. Weight loss can improve the quality of life of these patients before surgery.
To evaluate the effect of a meal-replacement diet on weight loss, body composition, and the improvement of the quality of life in obese women with knee osteoarthritis pending surgery.
One branch intervention study was performed over three months on 81 women with a body mass index greater than 30 kg/m2 with knee osteoarthritis before surgery. Patients received a hyperproteic meal-replacement diet with two bottles of an oral nutrition supplement in lunch and dinner (1,035 kcal). Anthropometric parameters, and body composition were measured. The quality of life was assessed by WOMAC and SF-36 test.
The mean age of the patients was 62.23 (8.50) years. The percentage of weight loss was 8.23% (4.04). An improvement in the SF-36 total score was observed (basal: 49.35 [20.41], three months: 58.71 [17.07], p < 0.01). There was an improvement in WOMAC test (basal: 49.24% [25.53], three months: 40.59% [21.76], p < 0.01). It was observed that a 10% improvement in the SF-36 test was independently related to weight loss (OR: 1.2 [1.03-1.36], p < 0.02) adjusted by age and changes in body composition.
In women with osteoarthritis of the knee treated with a meal-replacement diet, there is a significant decrease in weight and fat mass with a relative increase of the latter. There is an improvement in the quality of life according to SF-36 and WOMAC. There is an independent relationship between weight loss and SF-36 improvement.
膝关节骨关节炎在我们所处环境中是一种高患病率疾病，尤其是在女性中。体重减轻可改善这些患者手术前的生活质量。
评估代餐饮食对等待手术的肥胖膝关节骨关节炎女性体重减轻、身体成分及生活质量改善的影响。
对81名术前体重指数大于30kg/m²的膝关节骨关节炎女性进行了为期三个月的单组干预研究。患者午餐和晚餐接受含两瓶口服营养补充剂的高蛋白代餐饮食（1035千卡）。测量人体测量参数和身体成分。通过WOMAC和SF-36测试评估生活质量。
患者的平均年龄为62.23（8.50）岁。体重减轻百分比为8.23%（4.04）。观察到SF-36总分有所改善（基线：49.35[20.41]，三个月：58.71[17.07]，p<0.01）。WOMAC测试有所改善（基线：49.24%[25.53]，三个月：40.59%[21.76]，p<0.01）。观察到SF-36测试中10%的改善与体重减轻独立相关（比值比：1.2[1.03-1.36]，p<0.02），该结果经年龄和身体成分变化调整。
采用代餐饮食治疗的膝关节骨关节炎女性体重和脂肪量显著降低，瘦体重相对增加。根据SF-36和WOMAC评估，生活质量有所改善。体重减轻与SF-36改善之间存在独立关系。
