School of Optometry and Vision Science, Queensland University of Technology, Room D513, O Block, Victoria Park Road, Kelvin Grove 4059, Brisbane, Queensland, Australia.
Cont Lens Anterior Eye. 2018 Oct;41(5):452-454. doi: 10.1016/j.clae.2018.03.009. Epub 2018 Mar 21.
Bullous keratopathy is a pathological corneal condition that arises due to irreversible oedema associated with endothelial cell loss or dysfunction. Symptoms may vary from mild (transient blurred vision and increased glare from epithelial oedema) to severe (an acute and significant loss of vision associated with frank endothelial decompensation, and pain due to ruptured epithelial bullae). Possible treatments to restore vision and minimise pain include topical hypertonic agents, bandage contact lenses, superficial anterior corneal surgical procedures or penetrating full thickness or endothelial keratoplasty. This case report describes a rare presentation of painless, bilateral, asymmetric bullous keratopathy with severe vision loss in an elderly male with non-insulin dependent diabetes mellitus.
大疱性角膜病变是一种病理性角膜疾病,由于与内皮细胞丧失或功能障碍相关的不可逆转水肿而引起。症状可能从轻度(上皮水肿引起的短暂视力模糊和光敏感增加)到重度(与明显内皮失代偿相关的急性和显著视力丧失,以及由于上皮大疱破裂引起的疼痛)不等。可能的治疗方法包括局部高渗剂、绷带接触镜、浅层前角膜手术或穿透性全厚度或内皮角膜移植术,以恢复视力和减轻疼痛。本病例报告描述了一位老年男性非胰岛素依赖型糖尿病患者的罕见表现,即无痛性、双侧、不对称性大疱性角膜病变,伴有严重视力丧失。