Morrow Jessica, Curry David, Dooher Maeve, Woolsey Siobhan
Department of Urology, Belfast City Hospital, Department of Urology, Craigavon Area Hospital, Co. Down BT63 5QQ.
Ulster Med J. 2017 Sep;86(3):181-184. Epub 2017 Sep 12.
Iatrogenic ureteric injuries are a rare but serious complication of abdomino-pelvic surgery which can be associated with significant morbidity. 65-80% of ureteric trauma is only identified in the postoperative period. Current guidelines recommend stent insertion or urinary diversion via percutaneous nephrostomy. Good quality evidence on success and outcomes remains scant and the optimum treatment pathway unknown.
A retrospective review of all delayed presentation ureteric injuries treated in our unit between 2005 and 2013 was performed. Clinical, treatment and outcome data were collected in a custom proforma.
19 patients with 21 injured ureters met inclusion criteria. 16/19 (84.2%) injuries were sustained during gynaecological procedures with 10 (52.6%) of these during total abdominal hysterectomy. Suspected mechanisms from diagnostic studies was defined as partial transection in 9/21 (42.9%), complete transection in 3/21 (14.3%) and perforation in 1/21 (4.8%).Median time from injury to presentation was 16 days (IQR 7-25). 11/21 (52.4%) had successful stenting with a median time to stent placement of 25 days (IQR 18.5-42). Those with failed stenting had a median time to attempted stenting of 65 days (IQR 10-91.3). Those with successful stenting 3/11 (27.3%) had resolution requiring no further intervention. 6/11 (54.5%) required open reconstruction, with the remaining two patients unfit for reconstruction and managed with long term stents. With successful stenting median time to definitive surgery was 413 days (IQR 156-476).
Success rates for stenting are similar to those reported in the literature (55% vs. 44-59%), but resolution rates are significantly lower (15% vs. 44-80%). Data for an endourological approach as a possible long-term solution is limited by heterogeneity, and a further well conducted multicentre prospective study is required.
医源性输尿管损伤是腹部盆腔手术中一种罕见但严重的并发症,可能会导致严重的发病情况。65% - 80%的输尿管创伤在术后才被发现。目前的指南建议通过经皮肾造瘘术置入支架或进行尿液改道。关于成功率和治疗结果的高质量证据仍然很少,最佳治疗途径也尚不明确。
对2005年至2013年间在我们科室接受治疗的所有延迟发现的输尿管损伤进行回顾性研究。临床、治疗及结果数据通过定制表格收集。
19例患者共21条输尿管损伤符合纳入标准。19例中有16例(84.2%)损伤发生在妇科手术中,其中10例(52.6%)发生在全腹子宫切除术中。诊断性检查推测的损伤机制为部分横断9例(42.9%)、完全横断3例(14.3%)、穿孔1例(4.8%)。从受伤到出现症状的中位时间为16天(四分位间距7 - 25天)。21例中有11例(52.4%)支架置入成功,支架置入的中位时间为25天(四分位间距18.5 - 42天)。支架置入失败的患者尝试置入支架的中位时间为65天(四分位间距10 - 91.3天)。支架置入成功的患者中,3例(27.3%)症状缓解,无需进一步干预。6例(54.5%)需要进行开放重建,其余2例患者不适合重建,采用长期支架治疗。支架置入成功后,确定性手术的中位时间为413天(四分位间距156 - 476天)。
支架置入的成功率与文献报道相似(55%对44% - 59%),但缓解率显著较低(15%对44% - 80%)。作为一种可能的长期解决方案,腔内泌尿外科治疗方法的数据因异质性而受限,需要进一步开展多中心前瞻性研究。