肺移植治疗肺移植物抗宿主病后的肠壁积气
Pneumatosis intestinalis after lung transplantation for pulmonary graft-versus-host disease.
作者信息
Mesaki Kumi, Sugimoto Seiichiro, Otani Shinji, Kurosaki Takeshi, Miyoshi Kentaroh, Yamane Masaomi, Oto Takahiro
机构信息
Department of General Thoracic Surgery, Okayama University Hospital, Okayama, Japan.
Department of Organ Transplant Center, Okayama University Hospital, Okayama, Japan.
出版信息
J Thorac Dis. 2018 Jan;10(1):E42-E45. doi: 10.21037/jtd.2017.11.121.
Pneumatosis intestinalis, which could complicate a spectrum of clinical conditions ranging from benign to life-threatening, is a rarely encountered complication after lung transplantation (LT). We describe two cases in which PI developed as a complication following LT for pulmonary graft-versus-host disease (GVHD) after hematopoietic stem cell transplantation (HSCT). In addition to the long-term immunosuppression administered for pulmonary GVHD, the intense immunosuppression needed after LT might increase the risk of PI in lung transplant recipients after HSCT. Conservative therapy should be considered for the treatment of PI developing after LT.
肠壁积气可使一系列从良性到危及生命的临床状况复杂化，是肺移植（LT）后罕见的并发症。我们描述了两例在造血干细胞移植（HSCT）后因肺部移植物抗宿主病（GVHD）接受LT后发生肠壁积气作为并发症的病例。除了针对肺部GVHD进行的长期免疫抑制治疗外，LT后所需的强化免疫抑制可能会增加HSCT后肺移植受者发生肠壁积气的风险。对于LT后发生的肠壁积气，应考虑采用保守治疗。
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