Lam Alfred K
Cancer Molecular Pathology of School of Medicine, Griffith University, Gold Coast, Australia.
Methods Mol Biol. 2018;1756:1-6. doi: 10.1007/978-1-4939-7734-5_1.
Esophageal and esophagogastric adenocarcinoma is highly prevalent in the Western populations and is a major cause of cancer-related morbidity and mortality worldwide. The incidence of esophageal adenocarcinoma is rapidly rising in the Western populations. The major predisposing diseases and pathogenesis (gastro-esophageal reflux disease, Barrett esophagus, and dysplasia) of the cancer are well known. There is an urgent need for works of the multidisciplinary teams (clinical, pathological, the molecular biology and translational research) for improved outcomes of patients with this cancer.
食管及食管胃交界腺癌在西方人群中高度流行,是全球癌症相关发病和死亡的主要原因。在西方人群中,食管腺癌的发病率正在迅速上升。这种癌症的主要诱发疾病和发病机制(胃食管反流病、巴雷特食管和发育异常)已为人所知。迫切需要多学科团队(临床、病理、分子生物学和转化研究)开展工作,以改善这种癌症患者的治疗效果。