Patel Ankit, Ruparel Sameer, Dusad Tarun, Mehta Gaurav, Kundnani Vishal
Bombay Hospital, Mumbai, India.
J Neurosurg Pediatr. 2018 Jun;21(6):606-614. doi: 10.3171/2017.12.PEDS17404. Epub 2018 Mar 30.
OBJECTIVE Spinal osteotomy in pediatric patients is challenging due to various factors. For correction of severe rigid kyphoscoliosis in children, numerous techniques with anterior or posterior or combined approaches, as well as multilevel osteotomies, have been described. These techniques are associated with prolonged operative times and large amounts of blood loss. The purpose of this study was to evaluate the clinical and radiologically confirmed efficacy of a modification of the apical spinal osteotomy (ASO) technique-posterior-only single-level asymmetric closing osteotomy-in pediatric patients with severe rigid kyphoscoliosis. METHODS The authors performed a retrospective study of a case series involving pediatric patients with severe spinal deformity operated on by a single surgeon at a single institution over a period of approximately 5 years. The inclusion criteria were age < 14 years, rigid thoracic/thoracolumbar/lumbar kyphosis (> 70°) with or without neurological deficit and with or without scoliosis, and a minimum of 2 years of follow-up. Patients with cervical or lumbosacral kyphoscoliosis were excluded from the study. Demographic and clinical parameters, including age, sex, etiology of kyphoscoliosis, neurological examination status (Frankel grade), and visual analog scale (VAS) and Oswestry Disability Index (ODI) scores, were noted. Operative parameters (level of osteotomy, number of levels fused, duration of surgery, blood loss, and complications) were also recorded. Radiological assessment was done for preoperative and postoperative kyphosis and scoliosis as well as the final Cobb angle. Similarly, sagittal vertical axis (SVA) correction was calculated. Fusion was assessed in all patients at the final follow-up evaluation. RESULTS A total of 26 pediatric patients (18 male and 8 female) with a mean age of 9 years met the inclusion criteria and had data available for analysis, and all of these patients had severe scoliosis as well as kyphosis. Comparison of preoperative and postoperative values showed a significant improvement (p < 0.05) in radiological, clinical, and functional parameters (Cobb angle for scoliosis and kyphosis, SVA, VAS, and ODI). With respect to kyphosis, the mean preoperative Cobb angle was 96.54°, the mean postoperative angle was 30.77°, and the mean angle at final follow-up was 34.81° (average loss of correction of 4.23°), for a final average correction of 64.15%. With respect to scoliosis, the mean preoperative angle was 52.54°, the mean postoperative angle was 15.77°, and the mean angle at final follow-up was 19.42° (average loss of correction of 3.66°), for a final average correction of 60.95%. The preoperative SVA averaged 7.6 cm; the mean SVA improved to 3.94 cm at the end of 2 years. Bony fusion was achieved in all patients. The mean number of levels fused was 5.69. The mean operative time was 243.46 minutes, with an average intraoperative blood loss of 336.92 ml. Nonneurological complications occurred in 15.39% of patients (2 dural tears, 1 superficial infection, 1 implant failure). At the 2-year follow-up, 25 of the 26 patients had maintained or improved their neurological status. One patient developed paraplegia immediately after the operation and recovered only partially. CONCLUSIONS Analysis of data from this series of 26 cases indicates that this posterior-approach single-level technique is effective for the correction of severe rigid kyphoscoliosis in pediatric patients, providing good clinical and radiological results in most cases.
目的 由于多种因素,小儿患者的脊柱截骨术具有挑战性。对于矫正儿童严重僵硬性脊柱后凸畸形,已经描述了多种采用前路、后路或联合入路以及多级截骨的技术。这些技术与手术时间延长和大量失血相关。本研究的目的是评估改良的顶椎脊柱截骨术(ASO)技术——仅后路单节段不对称闭合截骨术——在小儿严重僵硬性脊柱后凸畸形患者中的临床和经放射学证实的疗效。方法 作者对一个病例系列进行了回顾性研究,该系列涉及在单一机构由一名外科医生在大约5年的时间里为小儿严重脊柱畸形患者实施手术的情况。纳入标准为年龄<14岁、有或无神经功能缺损且有或无脊柱侧凸的僵硬性胸段/胸腰段/腰段脊柱后凸(>70°),以及至少2年的随访。颈椎或腰骶部脊柱后凸畸形患者被排除在研究之外。记录人口统计学和临床参数,包括年龄、性别、脊柱后凸畸形的病因、神经学检查状况(Frankel分级)以及视觉模拟评分(VAS)和Oswestry功能障碍指数(ODI)评分。还记录手术参数(截骨水平、融合节段数、手术持续时间、失血量和并发症)。对术前和术后的脊柱后凸和脊柱侧凸以及最终的Cobb角进行放射学评估。同样,计算矢状垂直轴(SVA)矫正情况。在最终随访评估时对所有患者的融合情况进行评估。结果 共有26例小儿患者(18例男性和8例女性),平均年龄9岁,符合纳入标准且有可供分析的数据,所有这些患者均有严重脊柱侧凸以及脊柱后凸。术前和术后值的比较显示,放射学、临床和功能参数(脊柱侧凸和脊柱后凸的Cobb角、SVA、VAS和ODI)有显著改善(p<0.05)。关于脊柱后凸,术前平均Cobb角为96.54°,术后平均角度为30.77°,最终随访时平均角度为34.81°(平均矫正丢失4.23°),最终平均矫正率为64.15%。关于脊柱侧凸,术前平均角度为52.54°,术后平均角度为15.77°,最终随访时平均角度为19.42°(平均矫正丢失3.66°),最终平均矫正率为60.95%。术前SVA平均为7.6 cm;2年后平均SVA改善至3.94 cm。所有患者均实现了骨性融合。平均融合节段数为5.69。平均手术时间为243.46分钟,平均术中失血量为336.92 ml。15.39%的患者发生非神经学并发症(2例硬脊膜撕裂、1例浅表感染、1例植入物失败)。在2年随访时,26例患者中有25例神经状况维持或改善。1例患者术后立即发生截瘫,仅部分恢复。结论 对这一系列2.6例病例的数据分析表明,这种后路单节段技术对于矫正小儿严重僵硬性脊柱后凸畸形有效,在大多数情况下可提供良好的临床和放射学结果。