Kostenko V V, Kolot N V
Institute of Fundamental Medicine and Biology of Kazan (Volga Region) Federal University, 18, Kremlevskaya str, Kazan, 420008, Russian Federation;
V.N.Karazin Kharkiv National University, 4, Svobody sq., Kharkov, 61022, Ukraine.
Adv Gerontol. 2017;30(6):859-867.
It was analyzed a comparative study of age-dependent changes in the parameters of reproductive function and embryonic development of offspring from adults w1c-s, w1Or mutant strains and Canton-S, Oregon-R wild-type strains D. melanogaster. In investigation three age groups of adult drosophila: 3, 10 and 20-days old were used. Reciprocal crosses between young and aging parents enable to define the influence of age of the maternal and/or paternal organism on the parameters of reproductive function. It is shown that the various features of reproductive function in F1 offspring of mutants and wild-type strains are forming differently by the different influence of the age of parents. The established effect of the white mutation, either as an independent factor or in combination with the parental age, is reflected in the low values of the fertility and viability and high values of dominant lethal mutations and mortality on the metamorphosis stage and consequently the appearance of less adapt and viable offspring in the population.
对黑腹果蝇w1c-s、w1Or突变株系以及Canton-S、Oregon-R野生型株系成年果蝇后代的生殖功能参数和胚胎发育的年龄依赖性变化进行了比较研究。在研究中使用了三个年龄组的成年果蝇:3日龄、10日龄和20日龄。年轻亲本与老龄亲本之间的正反交能够确定母体和/或父体生物体年龄对生殖功能参数的影响。结果表明,由于亲本年龄的不同影响,突变株系和野生型株系F1后代生殖功能的各种特征形成方式不同。白色突变的既定效应,无论是作为独立因素还是与亲本年龄相结合,都反映在生育力和活力值较低以及显性致死突变和变态阶段死亡率较高,从而导致群体中适应性和活力较差的后代出现。