Department of Clinical Neurophysiology, Institute of Neurosciences, Uppsala University, Sweden.
Faculdade Medicina Sao Jose do Rio Preto, Investigation Neuromuscular Laboratory, Sao Jose do Rio Preto SP, Brazil.
J Neuromuscul Dis. 2018;5(2):225-230. doi: 10.3233/JND-170289.
Comparing results from jitter studies performed with voluntary and electrical activation is difficult to perform quantitatively, particularly in complex signals as seen in reinnervation. High jitter values in individual spikes in these multispike signals can be missed with both activation methods, which introduces a bias towards more normal values.With voluntary activation, triggering on a spike from an abnormal end-plate in multispike potentials will overestimate individual jitter values and the number of abnormal jitter values.With electrical stimulation, artefactually-increased jitter may be caused by subliminal stimulation, which causes uncertainty at the stimulation point. Electrical stimulation also may activate many axons, causing signal summation, with erroneous or impossible jitter estimation.Awareness of such pitfalls can improve the correct performance and interpretation of jitter recordings. Quantitative comparisons of results can be made between studies in reinnervated muscle performed with the same activation method, but not between results obtained with different activation methods.
比较使用自愿激活和电激活进行的微颤研究的结果是困难的，尤其是在复杂信号中，如再支配中所见。在这些多峰信号中，个别峰的高微颤值可能会被两种激活方法遗漏，这会导致偏向于更正常的值。使用自愿激活，在多峰电位中从异常终板触发一个峰会高估个别微颤值和异常微颤值的数量。用电刺激时，由于潜刺激引起的人为增加的微颤可能会导致刺激点不确定。电刺激也可能会激活许多轴突，导致信号叠加，从而导致错误或不可能的微颤估计。了解这些陷阱可以提高微颤记录的正确性能和解释。可以在使用相同激活方法的再支配肌肉的研究之间进行结果的定量比较，但不能在使用不同激活方法获得的结果之间进行比较。
