海豚科的蓝斑复合体。

Locus coeruleus complex of the family Delphinidae.

机构信息

Veterinary Histology and Pathology, Institute of Animal Health, University of Las Palmas de Gran Canaria, Veterinary School, Trasmontaña s/n, Arucas, Las Palmas, 35416, Spain.

Department of Veterinary Medical Science, University of Bologna, Ozzano dell'Emilia, Bologna, 40064, Italy.

出版信息

Sci Rep. 2018 Apr 3;8(1):5486. doi: 10.1038/s41598-018-23827-z.

The locus coeruleus (LC) is the largest catecholaminergic nucleus and extensively projects to widespread areas of the brain and spinal cord. The LC is the largest source of noradrenaline in the brain. To date, the only examined Delphinidae species for the LC has been a bottlenose dolphin (Tursiops truncatus). In our experimental series including different Delphinidae species, the LC was composed of five subdivisions: A6d, A6v, A7, A5, and A4. The examined animals had the A4 subdivision, which had not been previously described in the only Delphinidae in which this nucleus was investigated. Moreover, the neurons had a large amount of neuromelanin in the interior of their perikarya, making this nucleus highly similar to that of humans and non-human primates. This report also presents the first description of neuromelanin in the cetaceans' LC complex, as well as in the cetaceans' brain.

蓝斑（LC）是最大的儿茶酚胺能核团，广泛投射到大脑和脊髓的广泛区域。LC 是大脑中去甲肾上腺素的最大来源。迄今为止，唯一对 LC 进行检查的海豚科物种是宽吻海豚（Tursiops truncatus）。在我们包括不同海豚科物种的实验系列中，LC 由五个细分部分组成：A6d、A6v、A7、A5 和 A4。被检查的动物有 A4 细分部分，这在之前研究过的唯一海豚科物种中尚未描述过。此外，神经元的胞体内部有大量的神经黑色素，这使得该核团与人类和非人类灵长类动物非常相似。本报告还首次描述了鲸目动物 LC 复合体以及鲸目动物大脑中的神经黑色素。