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失眠障碍认知行为疗法对军人睡眠和共病症状的影响:一项随机临床试验。

Impact of cognitive behavioral therapy for insomnia disorder on sleep and comorbid symptoms in military personnel: a randomized clinical trial.

机构信息

Department of Psychology, University of North Texas, Denton, TX.

Department of Psychiatry, University of Texas Health Science Center at San Antonio, San Antonio, TX.

出版信息

Sleep. 2018 Jun 1;41(6). doi: 10.1093/sleep/zsy069.

DOI:10.1093/sleep/zsy069
PMID:29618098
Abstract

STUDY OBJECTIVES

To compare the efficacy of cognitive behavioral therapy for insomnia (CBTi) disorder and a Control condition on reducing insomnia and comorbid symptoms in a sample of active duty military personnel.

METHODS

Randomized clinical trial of 151 active duty US Army personnel at Fort Hood, Texas.

RESULTS

This study replicated Original (n = 66) findings (CBTi outperformed Control) in a follow-on sample (n = 85) on diary-assessed sleep efficiency (d = 1.04), total sleep time (d = 0.38), sleep latency (d = -0.93), number of awakenings (d = -0.56), wake time after sleep onset (d = -0.91), sleep quality (d = 1.00), and the Insomnia Severity Index (d = -1.36) in active duty soldiers. CBTi also outperformed Control in the combined sample (N = 151) on four of the five subscales of the Multidimensional Fatigue Inventory (d = -0.32 to -0.96) and the mental health subscale on the Veterans RAND 12-Item Health Survey (d = 0.37). Exploratory analyses also showed CBTi outperformed Control on nicotine (d = -0.22) and caffeine (d = -0.47) use reduction. Significant within-group differences were found for both groups on depression, anxiety, and posttraumatic stress disorder symptoms, but there was no group by time interaction for these symptoms or for use of hypnotics or alcohol.

CONCLUSIONS

CBTi was an effective treatment for insomnia and comorbid symptoms including daytime fatigue, general mental health, nicotine, and caffeine use.

CLINICAL TRIAL REGISTRATION

Clinicaltrials.gov; Identifier: NCT01549899; "Comparing Internet and In-Person Brief Cognitive Behavioral Therapy of Insomnia".

摘要

研究目的

比较认知行为疗法治疗失眠症(CBTi)障碍与对照条件对减少现役军人失眠症和共病症状的疗效。

方法

对德克萨斯州胡德堡的 151 名现役美国陆军人员进行随机临床试验。

结果

本研究在后续样本(n=85)中复制了原始研究(n=66)的发现(CBTi 优于对照),在日记评估的睡眠效率(d=1.04)、总睡眠时间(d=0.38)、睡眠潜伏期(d=-0.93)、觉醒次数(d=-0.56)、睡眠后醒来时间(d=-0.91)、睡眠质量(d=1.00)和失眠严重程度指数(d=-1.36)方面,现役士兵的结果相似。在接受 CBTi 和对照治疗的 151 名士兵中,CBTi 在多维疲劳量表(d=-0.32 至-0.96)的五个子量表中的四个以及退伍军人 RAND 12 项健康调查的心理健康子量表上也优于对照(d=0.37)。探索性分析还表明,CBTi 在减少尼古丁(d=-0.22)和咖啡因(d=-0.47)使用方面也优于对照。两组在抑郁、焦虑和创伤后应激障碍症状方面均有显著的组内差异,但两组在催眠药物和酒精使用方面均无组间时间交互作用。

结论

CBTi 是一种治疗失眠症和共病症状(包括白天疲劳、一般心理健康、尼古丁和咖啡因使用)的有效方法。

临床试验注册

Clinicaltrials.gov;标识符:NCT01549899;“比较互联网和现场简短认知行为疗法治疗失眠症”。

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