Gas chromatographic/mass spectrometric studies of the urinary metabolites of male rats given indan.
作者信息
Yu K O, Olson C T, Ferry M J, Serve M P
机构信息
Toxic Hazards Division, Harry G. Armstrong Aerospace Medical Research Laboratory, Wright-Patterson Air Force Base, Ohio 45433-6573.
出版信息
Biomed Environ Mass Spectrom. 1987 Nov;14(11):649-51. doi: 10.1002/bms.1200141114.
PMID:2962672
Abstract
The identified urinary metabolites of male rats exposed to indan are: 1- and 2-indanone; 1-, 2- and 5-indanol; 2- and 3-hydroxyl-1-indanone; and cis- and trans-indan-1,2-diol. Indan causes kidney damage in male rats in a manner similar to the cyclic hydrocarbons cis- and trans-decalin and JP-10. Lesions produced by indan occur only in male rats and not in female or control rats.
摘要
Zotero 插件