Di Marco Mariacristina, Rubbi Ivan, Baldi Agnese, Di Lorenzo Rosaria, Magnani Daniela, Cremonini Valeria, Sarli Leopoldo, Artioli Giovanna, Ferri Paola
Department of Specialist, Diagnostic and Experimental Medicine, Sant'Orsola - Malpighi Hospital, University of Bologna, Bologna, Italy.
School of Nursing, University of Bologna, Bologna, Italy.
Acta Biomed. 2018 Feb 27;89(4-S):18-27. doi: 10.23750/abm.v89i4-S.7063.
Cancer-related fatigue (CRF) is one of the most common symptoms experienced by cancer patients (CPs) and negatively affects quality of life. Although CRF is frequently experienced, it is often underreported, underdiagnosed and undertreated. The objectives of this study were to evaluate the level of fatigue in patients with pancreatic cancer undergoing chemotherapy and to analyse its correlation with patients' demographic and clinical variables.
A cross-sectional observational study was implemented in the Oncology Day Hospital of a Northern Italian hospital. A sample of 48 patients receiving chemotherapy were evaluated through the Brief Fatigue Inventory Italian version (BFI-I) between 1 May and 12 October 2016. Data were statistically analysed.
Most of our patients (94%) experienced fatigue. Women as well as patients with an age ≥65 years reported more fatigue. Anemia, pain and a weight loss of over 16 kg in the last 6 months were significantly related to the perception of fatigue. Regarding life habits, smoking was related to high global score of BFI-I.
In accordance with literature, our study suggests that fatigue is a frequent symptom influenced by many constitutional, clinical and environmental factors. Our results highlight the need for an early and regular evaluation of fatigue among cancer patients, in order to implement all those pharmacological and non-pharmacological interventions with proven efficacy in attenuating this symptom.
癌症相关疲劳（CRF）是癌症患者（CPs）最常经历的症状之一，对生活质量有负面影响。尽管CRF很常见，但往往报告不足、诊断不足和治疗不足。本研究的目的是评估接受化疗的胰腺癌患者的疲劳程度，并分析其与患者人口统计学和临床变量的相关性。
在意大利北部一家医院的肿瘤日间医院开展了一项横断面观察性研究。2016年5月1日至10月12日期间，通过意大利语版简易疲劳量表（BFI-I）对48例接受化疗的患者进行了评估。对数据进行了统计分析。
我们的大多数患者（94%）经历了疲劳。女性以及年龄≥65岁的患者报告的疲劳更多。贫血、疼痛以及过去6个月内体重减轻超过16 kg与疲劳感显著相关。关于生活习惯，吸烟与BFI-I的高总分相关。
与文献一致，我们的研究表明疲劳是一种常见症状，受许多体质、临床和环境因素影响。我们的结果强调需要对癌症患者的疲劳进行早期和定期评估，以便实施所有已证实对减轻该症状有效的药物和非药物干预措施。
