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经闭孔吊带手术治疗单纯性压力性尿失禁后膀胱过度活动症症状:一项横断面比较研究

Overactive Bladder Symptoms after Transobturator Sling Surgery for Pure Stress Urinary Incontinence: A Cross-Sectional Comparative Study.

作者信息

Pereira E Silva Ricardo, Gomes Olival Vanessa, Ponte Carolina, Palma Dos Reis José, Colaço João, Grilo Isabel, Nunes Filomena

机构信息

Department of Urology, Centro Hospitalar Lisboa Norte, Lisbon, Portugal.

Department of Gynecology and Obstetrics, Hospital de Vila Franca de Xira, Vila Franca de Xira, Portugal.

出版信息

Urol Int. 2018;100(4):428-433. doi: 10.1159/000488204. Epub 2018 Apr 12.

Abstract

INTRODUCTION

Transobturator tape (TOT) surgery has been associated with increased overactive bladder (OAB) although much controversy exists.

METHODS

In a cross-sectional study, women who underwent TOT surgery for pure stress incontinence (MonarcTM) answered the 6 questions of the symptom bother (SB) subscale of the OAB questionnaire - short form (OABq-SF) and an additional question regarding whether symptoms began after surgery. Women with SB score over the 4th quartile (≥30/100) were reassessed after a longer follow-up. Patients from primary care were recruited as controls.

RESULTS

We recruited 213 patients (135 in the TOT group and 78 age-adjusted controls). The mean age of operated patients was 58.7 ± 10.1 years with a mean follow-up of 25.9 ± 13.2 months. OABq-SF SB scores did not differ between the TOT group and controls (respectively, 18.5 ± 30 and 15.5 ± 6.7, p = 0.202). A total of 48% patients reported no relationship between symptoms and surgery. Highly symptomatic operated patients were reassessed after a longer follow-up (46.3 ± 10.6 months). The mean score in the second follow-up (n = 25) was not statistically different from the first assessment (46.4 ± 22.7 and 58.1 ± 19.8, p = 0.059).

CONCLUSIONS

Women who underwent TOT surgery did not show increased OAB SB scores when compared to controls. Our study suggests that OAB symptoms may thus be present but overlooked during initial clinical assessment.

摘要

引言

经闭孔尿道中段悬吊带术(TOT)手术与膀胱过度活动症(OAB)的增加有关,尽管存在很多争议。

方法

在一项横断面研究中,因单纯性压力性尿失禁接受TOT手术(MonarcTM)的女性回答了膀胱过度活动症问卷简表(OABq-SF)症状困扰(SB)子量表的6个问题,以及一个关于症状是否在手术后开始出现的附加问题。SB评分超过第4四分位数(≥30/100)的女性在更长时间的随访后重新进行评估。招募初级保健患者作为对照。

结果

我们招募了213名患者(TOT组135名,78名年龄匹配的对照)。手术患者的平均年龄为58.7±10.1岁,平均随访时间为25.9±13.2个月。TOT组和对照组的OABq-SF SB评分没有差异(分别为18.5±30和15.5±6.7,p = 0.202)。共有48%的患者报告症状与手术无关。症状严重的手术患者在更长时间的随访后(46.3±10.6个月)重新进行评估。第二次随访(n = 25)的平均评分与第一次评估没有统计学差异(46.4±22.7和58.1±19.8,p = 0.059)。

结论

与对照组相比,接受TOT手术的女性没有表现出OAB SB评分增加。我们的研究表明,OAB症状可能存在,但在初始临床评估中被忽视。

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