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妊娠期感染性心内膜炎的二尖瓣修复术。

Mitral valve repair in infective endocarditis during pregnancy.

作者信息

Tamura Takahiro, Yokota Shuichi

机构信息

Department of Anesthesiology, Nagoya University Graduate School of Medicine, Nagoya, Japan.

Division of Anesthesiology, ese Red Cross Nagoya Daiichi Hospital, Nagoya, Japan.

出版信息

Ann Card Anaesth. 2018 Apr-Jun;21(2):189-191. doi: 10.4103/aca.ACA_165_17.

DOI:10.4103/aca.ACA_165_17
PMID:29652283
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5914222/
Abstract

Infective endocarditis (IE) during pregnancy and subsequent cardiac surgery are rare and associated with a high risk of mortality for the mother and fetus. It is difficult to determine the right time for cardiac intervention when IE is diagnosed early in pregnancy. A 33-year-old previously healthy woman in the 11 week of pregnancy was diagnosed with IE and underwent surgical intervention. The cardiopulmonary bypass settings and the anesthetic drugs were carefully chosen. Although she was in good health, while being discharged, the fetus did not survive. Anesthesiologists prioritizing the mother's survival should aim to improve fetal outcomes in such cases.

摘要

妊娠期感染性心内膜炎(IE)及随后的心脏手术较为罕见,且母婴死亡风险很高。当在妊娠早期诊断出IE时,很难确定进行心脏干预的合适时机。一名33岁、既往健康的女性在妊娠11周时被诊断为IE并接受了手术干预。体外循环设置和麻醉药物均经过精心选择。尽管她身体状况良好,但出院时胎儿未能存活。在此类情况下,以母亲存活为首要目标的麻醉医生应致力于改善胎儿结局。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbe/5914222/41fdd1baab3c/ACA-21-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbe/5914222/41fdd1baab3c/ACA-21-189-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/dcbe/5914222/41fdd1baab3c/ACA-21-189-g001.jpg

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本文引用的文献

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Circulation. 2015 Oct 13;132(15):1435-86. doi: 10.1161/CIR.0000000000000296. Epub 2015 Sep 15.
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Ultrasound Obstet Gynecol. 2014 May;43(5):500-7. doi: 10.1002/uog.13275. Epub 2014 Apr 4.
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新生儿及婴儿的麻醉神经毒性
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Major congenital malformations after first-trimester exposure to ACE inhibitors.孕早期接触血管紧张素转换酶抑制剂后出现的严重先天性畸形。
N Engl J Med. 2006 Jun 8;354(23):2443-51. doi: 10.1056/NEJMoa055202.
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Angiotensin II receptor antagonist treatment during pregnancy.孕期使用血管紧张素II受体拮抗剂治疗。
Birth Defects Res A Clin Mol Teratol. 2005 Feb;73(2):123-30. doi: 10.1002/bdra.20102.
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Endocarditis during pregnancy.妊娠期心内膜炎
South Med J. 2003 Nov;96(11):1156-7. doi: 10.1097/01.SMJ.0000054503.18393.1E.
10
Benzodiazepine use in pregnancy and major malformations or oral cleft: meta-analysis of cohort and case-control studies.孕期使用苯二氮䓬类药物与重大畸形或口腔腭裂:队列研究和病例对照研究的荟萃分析
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