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中度早产儿的经口喂养方法及出院时间

Oral feeding practices and discharge timing for moderately preterm infants.

作者信息

Brumbaugh Jane E, Colaizy Tarah T, Saha Shampa, Van Meurs Krisa P, Das Abhik, Walsh Michele C, Bell Edward F

机构信息

Department of Pediatric and Adolescent Medicine, Mayo Clinic, Rochester, MN, USA.

Department of Pediatrics, University of Iowa, Iowa City, IA, USA.

出版信息

Early Hum Dev. 2018 May;120:46-52. doi: 10.1016/j.earlhumdev.2018.04.001. Epub 2018 Apr 11.

Abstract

BACKGROUND

Oral feeding skills of moderately preterm infants are not mature at birth.

AIMS

To establish the relationship between postmenstrual age at introduction of first oral feeding and attainment of full oral feeding and hospital discharge for moderately preterm infants.

STUDY DESIGN

Multicenter retrospective analysis of a prospective cohort of moderately preterm infants admitted to a Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network hospital.

SUBJECTS

6146 infants born at 29-33 weeks' gestation from January 2012 to November 2013.

OUTCOME MEASURES

Postmenstrual age at full oral feeding and at hospital discharge.

RESULTS

The median postmenstrual age at first oral feeding was 33.9 weeks (interquartile range 33.1-34.3). For each week earlier at first oral feeding, full oral feeding occurred 4.5 days earlier (p < 0.0001) and hospital stay was shortened by 3.4 days (p < 0.0001). Higher birth weight (p < 0.0001) and black maternal race (p = 0.0001) were associated with younger postmenstrual age at full oral feeding and at discharge.

CONCLUSION

Moderately preterm infants with earlier introduction of oral feeding achieved earlier full oral feeding and hospital discharge.

摘要

背景

中度早产婴儿出生时经口喂养技能不成熟。

目的

确定中度早产婴儿首次经口喂养时的孕龄与完全经口喂养及出院之间的关系。

研究设计

对 Eunice Kennedy Shriver 国家儿童健康与人类发展研究所新生儿研究网络医院收治的中度早产婴儿前瞻性队列进行多中心回顾性分析。

研究对象

2012 年 1 月至 2013 年 11 月期间出生孕周为 29 - 33 周的 6146 名婴儿。

观察指标

完全经口喂养时及出院时的孕龄。

结果

首次经口喂养时的中位孕龄为 33.9 周(四分位间距 33.1 - 34.3)。首次经口喂养每提前一周,完全经口喂养提前 4.5 天出现(p < 0.0001),住院时间缩短 3.4 天(p < 0.0001)。较高的出生体重(p < 0.0001)和黑人母亲种族(p = 0.0001)与完全经口喂养时及出院时较小的孕龄相关。

结论

较早开始经口喂养的中度早产婴儿能更早实现完全经口喂养并出院。

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