新生儿脐带血和血浆中人类心房利钠肽的浓度。

Concentrations of human atrial natriuretic peptide in the cord blood and the plasma of the newborn.

作者信息

Ito Y, Matsumoto T, Ohbu K, Kimura Y, Hayashi M, Matsuo H, Kato H, Yamashita F

机构信息

Department of Pediatrics, Kurume University, School of Medicine, Japan.

出版信息

Acta Paediatr Scand. 1988 Jan;77(1):76-8. doi: 10.1111/j.1651-2227.1988.tb10601.x.

DOI:10.1111/j.1651-2227.1988.tb10601.x

PMID:2967025

Abstract

Concentrations of human atrial natriuretic peptide (hANP) in the cord blood and the plasma were measured in 25 newborns. The level of hANP in 0 to 1 post-natal days (212.8 +/- 118.1 pg/ml; mean +/- SD) was significantly higher than that in cord blood (69.7 +/- 53.2 pg/ml) (p less than 0.005). There were no significant differences in the levels of hANP at the ages of 0 to 1, 4 and 6 post-natal days. The level of hANP did not show any significant correlation with urinary excretion of Na, urinary Na/Cr or Na/K ratios. Further evaluations should be made in order to clarify the role of hANP during the early post-natal period.

摘要

对25名新生儿的脐带血和血浆中的人心房利钠肽（hANP）浓度进行了测量。出生后0至1天的hANP水平（212.8±118.1 pg/ml；平均值±标准差）显著高于脐带血中的水平（69.7±53.2 pg/ml）（p<0.005）。出生后0至1天、4天和6天的hANP水平无显著差异。hANP水平与尿钠排泄、尿钠/肌酐或钠/钾比值均无显著相关性。为了阐明hANP在出生后早期的作用，应进行进一步评估。