果蝇中的电子自旋共振（EPR）与全身麻醉
Electron Spin Resonance (EPR) in Drosophila and General Anesthesia.
作者信息
Turin Luca, Skoulakis Efthimios M C
机构信息
Biomedical Science Research Center "Alexander Fleming", Vari, Greece.
Biomedical Science Research Center "Alexander Fleming", Vari, Greece.
出版信息
Methods Enzymol. 2018;603:115-128. doi: 10.1016/bs.mie.2018.01.020. Epub 2018 Mar 8.
Changes in electron spin content can be detected by X-band continuous-wave electron spin resonance (ESR, EPR) in Drosophila fruit flies without requiring the use of spin traps. The spin changes are related to cellular respiration and behave differently in anesthesia-resistant fly strains. We describe the method used in these measurements and its possible applications to the problem of the mechanism of general anesthesia.
在果蝇中，无需使用自旋捕获剂，通过X波段连续波电子自旋共振（ESR，EPR）就能检测到电子自旋含量的变化。自旋变化与细胞呼吸有关，并且在抗麻醉果蝇品系中的表现有所不同。我们描述了这些测量中所使用的方法及其在全身麻醉机制问题上的可能应用。
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