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[Descemet 膜内皮角膜移植术。适应症、手术技术、术后管理及文献综述]

[Descemet's Membrane Endothelial Keratoplasty. Indication, surgical technic, postoperative management and review of literature].

作者信息

Kocaba V, Damour O, Auxenfans C, Burillon C

机构信息

Service d'ophtalmologie, Pavillon C, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France; Université Claude Bernard Lyon 1, 69100 Villeurbanne, France; Banque de Cornée de Lyon, Pavillon I, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, 169856, Singapore.

Banque de Cornée de Lyon, Pavillon I, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France.

出版信息

J Fr Ophtalmol. 2018 Apr;41(4):368-381. doi: 10.1016/j.jfo.2017.12.005. Epub 2018 Apr 17.

DOI:10.1016/j.jfo.2017.12.005
PMID:29673628
Abstract

Endothelial keratoplasty is currently the preferred method for the treatment of endothelial dysfunctions and dystrophies. Descemet Membrane Endothelial Keratoplasty (DMEK), described by Gerrit Melles in 2006, is performed by selectively replacing the damaged endothelium with a healthy counterpart. It leads to a faster visual recovery and better refractive outcomes with a limited risk of rejection compared to Descemet's Stripping Automated Endothelial Keratosplasty (DSAEK), which includes a thin stromal layer. Open debate still exists between DMEK and DSAEK. This article aims to provide a literature review and enlighten the reader on the DMEK technique, its results and complications.

摘要

内皮角膜移植术目前是治疗内皮功能障碍和营养不良的首选方法。2006年由格里特·梅尔斯描述的后弹力层内皮角膜移植术(DMEK),是通过用健康的内皮替代受损的内皮来进行的。与包括薄基质层的后弹力层剥离自动内皮角膜移植术(DSAEK)相比,它能带来更快的视力恢复和更好的屈光效果,且排斥风险有限。DMEK和DSAEK之间仍存在公开的争论。本文旨在提供一篇文献综述,并让读者了解DMEK技术、其结果和并发症。

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引用本文的文献

1
Is ultra-thin Descemet stripping automated endothelial keratoplasty a viable alternative to Descemet membrane endothelial keratoplasty? A systematic review and meta-analysis.超薄Descemet膜剥除自动内皮角膜移植术是Descemet膜内皮角膜移植术的可行替代方案吗?一项系统评价和荟萃分析。
Ther Adv Ophthalmol. 2023 Feb 7;15:25158414221147823. doi: 10.1177/25158414221147823. eCollection 2023 Jan-Dec.
2
Descemet membrane endothelial keratoplasty (DMEK): an update on safety, efficacy and patient selection.后弹力层内皮角膜移植术(DMEK):安全性、有效性及患者选择的最新进展
Clin Ophthalmol. 2019 Aug 16;13:1549-1557. doi: 10.2147/OPTH.S178473. eCollection 2019.