[Descemet 膜内皮角膜移植术。适应症、手术技术、术后管理及文献综述]
[Descemet's Membrane Endothelial Keratoplasty. Indication, surgical technic, postoperative management and review of literature].
作者信息
Kocaba V, Damour O, Auxenfans C, Burillon C
机构信息
Service d'ophtalmologie, Pavillon C, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France; Université Claude Bernard Lyon 1, 69100 Villeurbanne, France; Banque de Cornée de Lyon, Pavillon I, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France; Tissue Engineering and Stem Cell Group, Singapore Eye Research Institute, 169856, Singapore.
Banque de Cornée de Lyon, Pavillon I, hôpital Édouard-Herriot, 5, place d'Arsonval, 69003 Lyon, France.
出版信息
J Fr Ophtalmol. 2018 Apr;41(4):368-381. doi: 10.1016/j.jfo.2017.12.005. Epub 2018 Apr 17.
Endothelial keratoplasty is currently the preferred method for the treatment of endothelial dysfunctions and dystrophies. Descemet Membrane Endothelial Keratoplasty (DMEK), described by Gerrit Melles in 2006, is performed by selectively replacing the damaged endothelium with a healthy counterpart. It leads to a faster visual recovery and better refractive outcomes with a limited risk of rejection compared to Descemet's Stripping Automated Endothelial Keratosplasty (DSAEK), which includes a thin stromal layer. Open debate still exists between DMEK and DSAEK. This article aims to provide a literature review and enlighten the reader on the DMEK technique, its results and complications.
内皮角膜移植术目前是治疗内皮功能障碍和营养不良的首选方法。2006年由格里特·梅尔斯描述的后弹力层内皮角膜移植术（DMEK），是通过用健康的内皮替代受损的内皮来进行的。与包括薄基质层的后弹力层剥离自动内皮角膜移植术（DSAEK）相比，它能带来更快的视力恢复和更好的屈光效果，且排斥风险有限。DMEK和DSAEK之间仍存在公开的争论。本文旨在提供一篇文献综述，并让读者了解DMEK技术、其结果和并发症。
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