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骨髓草酸沉着症:终末期肾病血细胞减少的罕见原因;两例报告。

Bone marrow oxalosis: An unusual cause of cytopenia in end-stage renal disease; report of two cases.

作者信息

Sharma Seema, Rao Ram Nawal, Pani Krushna Chandra, Paul Paramita

机构信息

Department of Pathology, SGPGIMS, Lucknow, Uttar Pradesh, India.

出版信息

Indian J Pathol Microbiol. 2018 Apr-Jun;61(2):268-270. doi: 10.4103/IJPM.IJPM_572_17.

Abstract

Systemic oxalosis can be either primary or secondary hyperoxaluria. Oxalosis is a phenomenon in which calcium oxalate crystals deposit in various visceral organs leading to bone marrow (BM) failure and recurrent renal stones. We describe two rare cases of BM oxalosis. Hyperoxaluria is strongly associated with nephrolithiasis and nephrocalcinosis. Both the patients presented with recurrent renal stones and a variable degree of BM failure. BM oxalosis should be considered as a possible diagnosis in patients in recurrent nephrolithiasis and cytopenia.

摘要

全身性草酸沉积症可分为原发性或继发性高草酸尿症。草酸沉积症是一种草酸钙晶体在各种内脏器官中沉积,导致骨髓(BM)衰竭和复发性肾结石的现象。我们描述了两例罕见的骨髓草酸沉积症病例。高草酸尿症与肾结石和肾钙质沉着症密切相关。两名患者均出现复发性肾结石和不同程度的骨髓衰竭。对于复发性肾结石和血细胞减少的患者,应考虑骨髓草酸沉积症作为一种可能的诊断。

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