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[合并多种疾病和/或使用抗血小板-抗凝药物的患者中黑色素瘤和非黑色素瘤皮肤癌的皮肤科手术并发症发生率。我院五年经验]

[Incidence of complications in dermatological surgery of melanoma and non-melanoma skin cancer in patients with multiple comorbidity and/or antiplatelet-anticoagulants. Five year experience in our Hospital].

作者信息

Arguello-Guerra Lilia, Vargas-Chandomid Estefanía, Díaz-González Jose Manuel, Méndez-Flores Silvia, Ruelas-Villavicencio Ana, Domínguez-Cherit Judith

机构信息

Departamento de Dermatología, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.

出版信息

Cir Cir. 2018;86(1):20-28. doi: 10.24875/CIRU.M18000012.

Abstract

INTRODUCTION

Surgery is performed more frequently now at days, due to the increasing incidence of melanoma and no-melanoma skin cancer. There are different opinions among dermatologic surgeons between to continue or discontinue antithrombotic therapy prior to the procedure, which increases the risk of thromboembolic events. Prophylaxis with oral antibiotics in the postsurgical period is controversial.

OBJECTIVE

To report the safety of surgery without suspending antithrombotic therapy and without oral antibiotic prophylaxis in dermatology surgery of patients with multiple comorbidities and polypharmacy.

METHOD

We designed a retrospective study. We included a total of 655 patients; 96.6% had at least one comorbidity; 27.7% used aspirin and 4.3% some type of antithrombotic therapy. The most common type of skin tumor was basal cell carcinoma with 69.8% .

RESULTS

The complication rate was 4.2%; the most was wound dehiscence (1.1%), followed by partial necrosis (0.9%), infection (0.9%), reaction to foreign body (0.6%), complete necrosis (0.3%), bleeding (0.2%) and fistulae (0.2%).

CONCLUSIONS

Based on the literature and our experience, dermatologic surgery is safe without suspending antithrombotic therapy or antibiotic prophylaxis in patients with multiple comorbidity.

摘要

引言

如今,由于黑色素瘤和非黑色素瘤皮肤癌的发病率不断上升,手术的实施频率越来越高。在手术前是否继续或停止抗血栓治疗这一问题上,皮肤科外科医生存在不同意见,因为这会增加血栓栓塞事件的风险。术后口服抗生素预防存在争议。

目的

报告在患有多种合并症且使用多种药物的患者进行皮肤科手术时,不暂停抗血栓治疗且不进行口服抗生素预防的手术安全性。

方法

我们设计了一项回顾性研究。共纳入655例患者;96.6%至少有一种合并症;27.7%使用阿司匹林,4.3%使用某种类型的抗血栓治疗。最常见的皮肤肿瘤类型是基底细胞癌,占69.8%。

结果

并发症发生率为4.2%;最常见的是伤口裂开(1.1%),其次是部分坏死(0.9%)、感染(0.9%)、异物反应(0.6%)、完全坏死(0.3%)、出血(0.2%)和瘘管(0.2%)。

结论

根据文献和我们的经验,对于患有多种合并症的患者,在不暂停抗血栓治疗或抗生素预防的情况下进行皮肤科手术是安全的。

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