由于 W 群侵袭性脑膜炎奈瑟菌疾病的持续增加，荷兰于 2018 年实施 MenACWY 疫苗接种。
Implementation of MenACWY vaccination because of ongoing increase in serogroup W invasive meningococcal disease, the Netherlands, 2018.
机构信息
Center for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, the Netherlands.
Netherlands Reference Laboratory for Bacterial Meningitis, Academic Medical Center, Amsterdam, the Netherlands.
出版信息
Euro Surveill. 2018 Apr;23(16). doi: 10.2807/1560-7917.ES.2018.23.16.18-00158.
The annual incidence rate of serogroup W invasive meningococcal disease in the Netherlands increased from < 0.05/100,000 (n < 10) before 2015 to 0.5/100,000 (n = 80) in 2017. Most isolates (94%) belong to clonal complex 11. The incidence rate is highest among < 5 year-olds and 15-24 year-olds. The case fatality rate was 12% (17/138) in 2015-2017. From May 2018, MenACWY vaccination replaces MenC vaccination at age 14 months and from October 2018, 13-14 year-olds are offered MenACWY vaccination.
在荷兰，血清群 W 侵袭性脑膜炎球菌病的年发病率从 2015 年之前的每 10 万人中 <0.05 例（n<10）上升至 2017 年的每 10 万人中 0.5 例（n=80）。大多数分离株（94%）属于克隆复合体 11。发病率在 5 岁以下和 15-24 岁人群中最高。2015-2017 年的病死率为 12%（17/138）。自 2018 年 5 月起，14 个月大的婴儿开始接种 MenACWY 疫苗，取代 MenC 疫苗，自 2018 年 10 月起，13-14 岁的青少年也可以接种 MenACWY 疫苗。
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