Walayat Saqib, Hussain Nooreen, Malik Abdullah H, Vazquez-Melendez Elsa, Aulakh Bhagat S, Lynch Teresa
Department of Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Department of Pulmonary/Critical Care Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Int Med Case Rep J. 2018 Apr 12;11:87-90. doi: 10.2147/IMCRJ.S154807. eCollection 2018.
, a Gram-negative diplococcus, is an uncommon cause of pneumonia. There have been only about 344 cases reported worldwide from 1906 to 2015. To our knowledge, there have been only 3 cases reported in the USA in the past 2 decades. We present a case of a 72-year-old male with a past medical history of severe COPD, obstructive sleep apnea, and stage I lung cancer status post-stereotactic body radiation therapy 1 year ago, who was admitted with a 6-day history of productive cough with yellowish sputum, shortness of breath, extreme myalgias, and fatigue. Chest X-ray revealed an infiltrative process in the left lower lung field and left-sided pleural effusion. Blood cultures grew beta-lactamase-negative after 24 hours. Our patient was initially treated with broad-spectrum antibiotics, which were later switched to amoxicillin to complete a total of 14 days of antibiotics. Diagnosing meningococcal pneumonia requires a high level of suspicion, as sputum cultures may be falsely positive due to asymptomatic carriage of the organism in the upper respiratory tract in up to 10% of outpatient population. We highlight this case as early recognition and treatment is critical. The case fatality rate for pneumonia has been reported to be higher compared with meningococcal meningitis.
革兰氏阴性双球菌是肺炎的一种罕见病因。从1906年到2015年,全球仅报告了约344例病例。据我们所知,在过去20年中,美国仅报告了3例。我们报告一例72岁男性患者,既往有严重慢性阻塞性肺疾病、阻塞性睡眠呼吸暂停病史,1年前接受立体定向体部放射治疗后处于I期肺癌状态,因咳嗽、咳黄色痰6天、气短、极度肌痛和疲劳入院。胸部X线显示左下肺野浸润性病变及左侧胸腔积液。血培养24小时后培养出β-内酰胺酶阴性的[具体细菌名称未给出]。我们的患者最初接受广谱抗生素治疗,后来改用阿莫西林,共使用抗生素14天。诊断脑膜炎球菌性肺炎需要高度怀疑,因为在高达10%的门诊人群中,由于该菌在上呼吸道无症状携带,痰培养可能出现假阳性。我们强调该病例,因为早期识别和治疗至关重要。据报道,脑膜炎球菌性肺炎的病死率高于脑膜炎球菌性脑膜炎。