Wang Chengjun, Zhao Meng, Wang Jia, Wang Shuo, Jiang Zhongli, Zhao Jizong
1 Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
2 China National Clinical Research Center for Neurological Diseases, Beijing, China.
J Child Neurol. 2018 Jul;33(8):512-518. doi: 10.1177/0883073818768156. Epub 2018 Apr 26.
The purpose of this study is to investigate the clinical manifestations, surgical treatment, and neurologic outcomes of frontal lobe cavernous malformations in children. A retrospective analysis of 23 pediatric frontal lobe cavernous malformation patients who underwent surgical treatment in Beijing Tiantan Hospital was performed. The case series included 16 boys and 7 girls. Gross total removal without surgical mortality was achieved in all patients. The mean follow-up period after surgery was 33.1 months. Two patients who left hospital with motor deficits gradually recovered after rehabilitative treatment, and other patients were considered to be in excellent clinical condition. For symptomatic frontal lobe cavernous malformations, neurosurgical management should be the treatment of choice. Conservative treatment may be warranted in asymptomatic frontal lobe cavernous malformations, especially the deep-seated or eloquently located cases.
本研究旨在探讨儿童额叶海绵状血管畸形的临床表现、手术治疗及神经功能预后。对在北京天坛医院接受手术治疗的23例儿童额叶海绵状血管畸形患者进行了回顾性分析。该病例系列包括16名男孩和7名女孩。所有患者均实现了全切且无手术死亡。术后平均随访期为33.1个月。两名出院时存在运动功能障碍的患者经康复治疗后逐渐恢复，其他患者临床状况良好。对于有症状的额叶海绵状血管畸形，神经外科治疗应作为首选。对于无症状的额叶海绵状血管畸形，尤其是深部或位于功能区的病例，可考虑保守治疗。
