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冠状动脉夹层血栓形成所致左主支休克综合征的成功治疗:一例报告

Successful treatment of left main shock syndrome induced by thrombosed coronary artery dissection: A case report.

作者信息

Bai Xiaojun, Zhang Weiping, Yuan Zuyi

机构信息

Department of Cardiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.

出版信息

Medicine (Baltimore). 2018 Apr;97(17):e0496. doi: 10.1097/MD.0000000000010496.

DOI:10.1097/MD.0000000000010496
PMID:29703012
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5944530/
Abstract

RATIONALE

Left main shock syndrome (LMSS) induced by thrombosed coronary artery dissection is very rare and has a fatal prognosis. Optimal treatment strategy includes early reperfusion and hemodynamic support to prevent cardiogenic shock. However, it involves the extension of technical difficulties under different conditions.

PATIENT CONCERNS

A 49-year-old woman developed symptoms of left main shock syndrome. The main clinical manifestations were retrosternal pain radiating to his back and left shoulder, heavy sweating, palpitation and brachypnea.

DIAGNOSES

Acute anterioseptal myocardial infarction (Killip Class IV) with cardiogenic shock and arrhythmia including ventricular tachycardia and idionodal rhythm, and coronary artery dissection.

INTERVENTIONS

A thrombus aspiration procedure was performed for the establishment of coronary flow under intra-aortic balloon pumping (IABP) support. Her coronary angiographic finding demonstrated a dissection in the mid-distal segment of the left main coronary artery where a sirolimus-eluting stent was deployed. Then, the veno-arterial extra-corporal membrane oxygenation (ECMO) was placed to improve severe cardiac dysfunction and end-organ failure.

OUTCOMES

The patient had a good outcome without active symptoms.

LESSONS

Thrombosis on the basis of coronary dissection is a very rare cause of LMSS. Successful team treatments, including the prompt thrombus aspiration and stent repair of artery dissection, potent IABP and ECMO support are important to improve the clinical outcome.

摘要

原理

冠状动脉夹层形成血栓所致的左主干休克综合征(LMSS)非常罕见,预后凶险。最佳治疗策略包括早期再灌注和血流动力学支持以预防心源性休克。然而,这在不同情况下会增加技术难度。

患者情况

一名49岁女性出现左主干休克综合征症状。主要临床表现为胸骨后疼痛放射至背部和左肩、大汗、心悸和呼吸急促。

诊断

急性前间隔心肌梗死(Killip分级IV级)伴心源性休克及心律失常,包括室性心动过速和结性心律,以及冠状动脉夹层。

干预措施

在主动脉内球囊反搏(IABP)支持下进行血栓抽吸术以建立冠状动脉血流。她的冠状动脉造影显示左主干冠状动脉中远段夹层,在此处植入了西罗莫司洗脱支架。然后,放置静脉-动脉体外膜肺氧合(ECMO)以改善严重的心功能不全和终末器官功能衰竭。

结果

患者预后良好,无明显症状。

经验教训

冠状动脉夹层基础上的血栓形成是LMSS非常罕见的病因。成功的团队治疗,包括及时的血栓抽吸和动脉夹层的支架修复以及有效的IABP和ECMO支持,对于改善临床结局很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/ff2283038289/medi-97-e0496-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/d8da4d44a4d9/medi-97-e0496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/dad84d7ce98e/medi-97-e0496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/ff2283038289/medi-97-e0496-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/d8da4d44a4d9/medi-97-e0496-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/dad84d7ce98e/medi-97-e0496-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/ff2283038289/medi-97-e0496-g003.jpg

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本文引用的文献

1
ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation.ST段抬高型急性心肌梗死患者管理的欧洲心脏病学会指南
Eur Heart J. 2012 Oct;33(20):2569-619. doi: 10.1093/eurheartj/ehs215. Epub 2012 Aug 24.
2
Extracorporeal membrane oxygenation-assisted primary percutaneous coronary intervention may improve survival of patients with acute myocardial infarction complicated by profound cardiogenic shock.体外膜肺氧合辅助经皮冠状动脉介入治疗可能改善急性心肌梗死并发深度心源性休克患者的生存。
J Crit Care. 2012 Oct;27(5):530.e1-11. doi: 10.1016/j.jcrc.2012.02.012. Epub 2012 May 15.
3
Emergency coronary artery bypass grafting for left main shock syndrome.
Ann Thorac Cardiovasc Surg. 2011;17(6):565-9. doi: 10.5761/atcs.oa.10.01645. Epub 2011 Jul 27.
4
Manual aspiration thrombectomy in acute ST elevation myocardial infarction: New gold standard.急性ST段抬高型心肌梗死的手动抽吸血栓切除术:新的金标准。
World J Cardiol. 2011 Feb 26;3(2):43-7. doi: 10.4330/wjc.v3.i2.43.
5
PCI for LMCA stenosis--is it time to ride the rank bull?
Catheter Cardiovasc Interv. 2006 Sep;68(3):363-4. doi: 10.1002/ccd.20806.
6
Long-term outcomes after stenting of bifurcation lesions with the "crush" technique: predictors of an adverse outcome.采用“挤压”技术对分叉病变进行支架置入后的长期预后:不良预后的预测因素
J Am Coll Cardiol. 2006 May 16;47(10):1949-58. doi: 10.1016/j.jacc.2005.11.083. Epub 2006 Apr 24.
7
Normal angiogram in patients with acute coronary syndrome: searching for unusual substrates of myocardial ischemia.急性冠状动脉综合征患者的正常血管造影:寻找心肌缺血的异常底物
Int J Cardiol. 2005 Mar 10;99(1):25-7. doi: 10.1016/j.ijcard.2004.03.089.
8
Cardiogenic shock complicating acute myocardial infarction: expanding the paradigm.急性心肌梗死并发心源性休克:拓展范例
Circulation. 2003 Jun 24;107(24):2998-3002. doi: 10.1161/01.CIR.0000075927.67673.F2.
9
Diagnosis and management of aortic dissection.主动脉夹层的诊断与管理
Eur Heart J. 2001 Sep;22(18):1642-81. doi: 10.1053/euhj.2001.2782.
10
Early revascularization in acute myocardial infarction complicated by cardiogenic shock. SHOCK Investigators. Should We Emergently Revascularize Occluded Coronaries for Cardiogenic Shock.急性心肌梗死合并心源性休克时的早期血运重建。SHOCK研究组。对于心源性休克,我们是否应紧急对闭塞冠状动脉进行血运重建。
N Engl J Med. 1999 Aug 26;341(9):625-34. doi: 10.1056/NEJM199908263410901.