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冠状动脉夹层血栓形成所致左主支休克综合征的成功治疗:一例报告

Successful treatment of left main shock syndrome induced by thrombosed coronary artery dissection: A case report.

作者信息

Bai Xiaojun, Zhang Weiping, Yuan Zuyi

机构信息

Department of Cardiology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China.

出版信息

Medicine (Baltimore). 2018 Apr;97(17):e0496. doi: 10.1097/MD.0000000000010496.

Abstract

RATIONALE

Left main shock syndrome (LMSS) induced by thrombosed coronary artery dissection is very rare and has a fatal prognosis. Optimal treatment strategy includes early reperfusion and hemodynamic support to prevent cardiogenic shock. However, it involves the extension of technical difficulties under different conditions.

PATIENT CONCERNS

A 49-year-old woman developed symptoms of left main shock syndrome. The main clinical manifestations were retrosternal pain radiating to his back and left shoulder, heavy sweating, palpitation and brachypnea.

DIAGNOSES

Acute anterioseptal myocardial infarction (Killip Class IV) with cardiogenic shock and arrhythmia including ventricular tachycardia and idionodal rhythm, and coronary artery dissection.

INTERVENTIONS

A thrombus aspiration procedure was performed for the establishment of coronary flow under intra-aortic balloon pumping (IABP) support. Her coronary angiographic finding demonstrated a dissection in the mid-distal segment of the left main coronary artery where a sirolimus-eluting stent was deployed. Then, the veno-arterial extra-corporal membrane oxygenation (ECMO) was placed to improve severe cardiac dysfunction and end-organ failure.

OUTCOMES

The patient had a good outcome without active symptoms.

LESSONS

Thrombosis on the basis of coronary dissection is a very rare cause of LMSS. Successful team treatments, including the prompt thrombus aspiration and stent repair of artery dissection, potent IABP and ECMO support are important to improve the clinical outcome.

摘要

原理

冠状动脉夹层形成血栓所致的左主干休克综合征(LMSS)非常罕见,预后凶险。最佳治疗策略包括早期再灌注和血流动力学支持以预防心源性休克。然而,这在不同情况下会增加技术难度。

患者情况

一名49岁女性出现左主干休克综合征症状。主要临床表现为胸骨后疼痛放射至背部和左肩、大汗、心悸和呼吸急促。

诊断

急性前间隔心肌梗死(Killip分级IV级)伴心源性休克及心律失常,包括室性心动过速和结性心律,以及冠状动脉夹层。

干预措施

在主动脉内球囊反搏(IABP)支持下进行血栓抽吸术以建立冠状动脉血流。她的冠状动脉造影显示左主干冠状动脉中远段夹层,在此处植入了西罗莫司洗脱支架。然后,放置静脉-动脉体外膜肺氧合(ECMO)以改善严重的心功能不全和终末器官功能衰竭。

结果

患者预后良好,无明显症状。

经验教训

冠状动脉夹层基础上的血栓形成是LMSS非常罕见的病因。成功的团队治疗,包括及时的血栓抽吸和动脉夹层的支架修复以及有效的IABP和ECMO支持,对于改善临床结局很重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5300/5944530/d8da4d44a4d9/medi-97-e0496-g001.jpg

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