Martell-Claros N, Abad-Cardiel M
Unidad de Hipertensión, Servicio de Medicina Interna, Hospital Clínico San Carlos, Madrid, España; Instituto de Investigación Sanitaria, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, España.
Unidad de Hipertensión, Servicio de Medicina Interna, Hospital Clínico San Carlos, Madrid, España; Instituto de Investigación Sanitaria, Hospital Clínico San Carlos, Facultad de Medicina, Universidad Complutense, Madrid, España.
Hipertens Riesgo Vasc. 2017 Jan;34 Suppl 1:25-28. doi: 10.1016/S1889-1837(18)30060-6.
When treating a patient with resistant hypertension therapy should be optimize in order to prescribe three antihypertensive drugs at full doses, being powerful drugs, having 24-hour coverage, and showing synergistic effects. Diuretic therapy is of special relevance. The fourth drug should be an aldosterone antagonists. In the case of intolerance, or when control is not achieved, drugs from other type of antihypertensive drugs should be, sometimes allowing adequate blood pressure control.