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比较上气道刺激与扩张括约肌咽成形术:一所大学的单中心经验

Comparing Upper Airway Stimulation to Expansion Sphincter Pharyngoplasty: A Single University Experience.

作者信息

Huntley Colin, Chou David W, Doghramji Karl, Boon Maurits

机构信息

1 Department of Otolaryngology, Head & Neck Surgery, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

2 Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.

出版信息

Ann Otol Rhinol Laryngol. 2018 Jun;127(6):379-383. doi: 10.1177/0003489418771395. Epub 2018 Apr 30.

DOI:10.1177/0003489418771395
PMID:29707958
Abstract

INTRODUCTION

Expansion sphincter pharyngoplasty (ESP) is a surgical option for patients with obstructive sleep apnea (OSA). Upper airway stimulation (UAS) is an alternative that has shown success in initial outcomes studies. We compare outcomes of a cohort of patients undergoing UAS to ESP.

METHODS

We compared demographic and polysomnographic data of the UAS to ESP cohorts. We also calculated the proportion of patients achieving surgical success.

RESULTS

The ESP cohort consisted of 33 patients. The mean preoperative Apnea-Hypopnea Index (AHI), O nadir, Epworth Sleepiness Scale (ESS), and BMI were 36.47 ± 20.01, 82.63 ± 5.37, 10.69 ± 4.42, and 29.6 ± 4.49, which improved to 13.47 ± 18.74, 84.84 ± 5.48, 7.00 ± 5.81, and 29.92 ± 4.59 postoperatively. There was a 63.64% success rate. The UAS cohort consisted of 75 patients. The mean preoperative AHI, O nadir, ESS, and BMI were 36.76 ± 20.72, 80.24 ± 8.43, 11.18 ± 4.16, and 29.50 ± 3.96, which improved to 7.25 ± 11.19, 88.71 ± 3.25, 5.36 ± 3.35, and 29.36 ± 3.68 postoperatively. The success rate was 86.67%. We found a significant difference in gender, age, preoperative AHI, postoperative AHI, postoperative O nadir, surgical success, and patients reaching an AHI less than 10 and 5.

CONCLUSION

Upper airway stimulation is a new surgical option for select patients with OSA showing comparable or improved outcomes to a cohort of patients undergoing ESP.

摘要

引言

扩张括约肌咽成形术(ESP)是阻塞性睡眠呼吸暂停(OSA)患者的一种手术选择。上气道刺激(UAS)是一种替代方法,在初始疗效研究中已显示出成功。我们比较了接受UAS和ESP治疗的一组患者的疗效。

方法

我们比较了UAS组和ESP组的人口统计学和多导睡眠图数据。我们还计算了手术成功患者的比例。

结果

ESP组由33例患者组成。术前平均呼吸暂停低通气指数(AHI)、最低血氧饱和度(O nadir)、爱泼华嗜睡量表(ESS)和体重指数(BMI)分别为36.47±20.01、82.63±5.37、10.69±4.42和29.6±4.49,术后分别改善至13.47±18.74、84.84±5.48、7.00±5.81和29.92±4.59。成功率为63.64%。UAS组由75例患者组成。术前平均AHI、O nadir、ESS和BMI分别为36.76±20.72、80.24±8.43、11.18±4.16和29.50±3.96,术后分别改善至7.25±11.19、88.71±3.25、5.36±3.35和29.36±3.68。成功率为86.67%。我们发现两组在性别、年龄、术前AHI、术后AHI、术后O nadir、手术成功率以及AHI小于10和5的患者数量方面存在显著差异。

结论

上气道刺激是部分OSA患者的一种新的手术选择,与接受ESP治疗的一组患者相比,其疗效相当或有所改善。

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