氧鎓铵树脂作为无金属、高反应性、多功能的聚合物氧化试剂。

Oxoammonium Resins as Metal-Free, Highly Reactive, Versatile Polymeric Oxidation Reagents.

作者信息

Weik Steffen, Nicholson Graeme, Jung Günther, Rademann Jörg

机构信息

Institut für Organische Chemie, Universität Tübingen Auf der Morgenstelle 18, 72076 Tübingen (Germany) Fax: (+49) 7071-295560.

出版信息

Angew Chem Int Ed Engl. 2001 Apr 17;40(8):1436-1439. doi: 10.1002/1521-3773(20010417)40:8<1436::AID-ANIE1436>3.0.CO;2-X.

DOI:10.1002/1521-3773(20010417)40:8<1436::AID-ANIE1436>3.0.CO;2-X

PMID:29712368

Abstract

Polymer-supported oxidation of alcohols was conducted very efficiently by employing oxoammonium salts, the reactive intermediates in TEMPO oxidations (TEMPO=2,2,6,6-tetramethylpiperidinoxyl). These highly reactive salts (see scheme; X=Br, Cl) could be prepared and isolated on the polymeric support, and were used for the conversion of single compounds as well as of complex mixtures of alcohols.

摘要

通过使用氧鎓盐（TEMPO氧化反应中的活性中间体，TEMPO = 2,2,6,6 - 四甲基哌啶氮氧化物），可非常有效地进行聚合物负载的醇氧化反应。这些高活性盐（见反应式；X = Br，Cl）可在聚合物载体上制备并分离出来，用于单一化合物以及醇的复杂混合物的转化。