Sikhondze Nomvuselelo, Mahomed Ozayr Haroon
Discipline of Public Health Medicine, University of KwaZulu Natal, Durban, South Africa.
Pan Afr Med J. 2017 Dec 26;28:316. doi: 10.11604/pamj.2017.28.316.13857. eCollection 2017.
Significant progress has been made with respect to the initiation of children on antiretroviral therapy (ART) in Southern Africa including Swaziland, however retention of these children in care poses a major challenge. The aim of the study was to assess retention to care in children testing HIV positive taking into account the number of return child welfare care (CWC) visits the child made.
A retrospective cross sectional study and was conducted at 4 facilities in Swaziland. All children who were HIV infected from 0 to 18 months were identified using the child welfare register (CWC). Infant characteristics were obtained from the child welfare register and early infant diagnosis logbooks. Proportion of patients retained in care were calculated at three, six, nine and twelve months.
Of the 32 HIV positive children identified tested between December 2014 up to July 2016, sixty eight percent (n = 22) of the children that tested HIV positive were retained at three months, 40.6% at six months, 18.8% at nine months and 12.5% at twelve months. Children that resided in urban areas, more male than female children, children from mothers who were on antiretroviral treatment, children initiated on antiretroviral treatment, mothers on antiretroviral treatment for more than one year and children who received Infant Nevirapine were more likely to be retained.
Facilities are performing well in terms of identifying HIV positive children within the first two months of life and linking them into care. However, as time progresses the retention of children in care declines. Innovative strategies need to be developed to enhance patient retention.
在包括斯威士兰在内的南部非洲,儿童抗逆转录病毒疗法(ART)的启动已取得显著进展,然而让这些儿童持续接受治疗却面临重大挑战。本研究的目的是评估感染艾滋病毒的儿童持续接受治疗的情况,同时考虑儿童返回儿童福利护理(CWC)就诊的次数。
在斯威士兰的4个机构进行了一项回顾性横断面研究。使用儿童福利登记册(CWC)确定所有0至18个月感染艾滋病毒的儿童。从儿童福利登记册和早期婴儿诊断日志中获取婴儿特征。计算在3个月、6个月、9个月和12个月时持续接受治疗的患者比例。
在2014年12月至2016年7月期间确定检测的32名艾滋病毒阳性儿童中,68%(n = 22)的艾滋病毒检测呈阳性儿童在3个月时持续接受治疗,6个月时为40.6%,9个月时为18.8%,12个月时为12.5%。居住在城市地区的儿童、男性儿童多于女性儿童、母亲接受抗逆转录病毒治疗的儿童、开始接受抗逆转录病毒治疗的儿童、母亲接受抗逆转录病毒治疗超过一年的儿童以及接受婴儿奈韦拉平治疗的儿童更有可能持续接受治疗。
各机构在识别出生后两个月内的艾滋病毒阳性儿童并使其接受治疗方面表现良好。然而,随着时间的推移,儿童持续接受治疗的比例下降。需要制定创新策略以提高患者的持续治疗率。