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验证一个自动生成的虚弱筛查评分的有效性:照顾需求评估(CAN)评分。

Validation of an automatically generated screening score for frailty: the care assessment need (CAN) score.

机构信息

Veterans' Successful Aging for Frail Elders (VSAFE) Program, Miami VA Healthcare System Geriatric Research Education and Clinical Center (GRECC), Bruce W. Carter Miami VAMC, 11 GRC, 1201 NW 16th Street, Miami, Florida, 33125, USA.

University of Miami Miller School of Medicine, Miami, Florida, USA.

出版信息

BMC Geriatr. 2018 May 4;18(1):106. doi: 10.1186/s12877-018-0802-7.

Abstract

BACKGROUND

Frailty is a state of vulnerability to stressors that is prevalent in older adults and is associated with higher morbidity, mortality and healthcare utilization. Multiple instruments are used to measure frailty; most are time-consuming. The Care Assessment Need (CAN) score is automatically generated from electronic health record data using a statistical model. The methodology for calculation of the CAN score is consistent with the deficit accumulation model of frailty. At a 95 percentile, the CAN score is a predictor of hospitalization and mortality in Veteran populations. The purpose of this study was to validate the CAN score as a screening tool for frailty in primary care.

METHODS

This is a cross-sectional, validation study compared the CAN score with a 40-item Frailty Index reference standard based on a comprehensive geriatric assessment. We included community-dwelling male patients over age 65 from an outpatient geriatric medicine clinic. We calculated the sensitivity, specificity, positive predictive value, negative predictive value and diagnostic accuracy of the CAN score.

RESULTS

184 patients over age 65 were included in the study: 97.3% male, 64.2% White, 80.9% non-Hispanic. The CGA-based Frailty Index defined 14.1% as robust, 53.3% as prefrail and 32.6% as frail. For the frail, statistical analysis demonstrated that a CAN score of 55 provides sensitivity, specificity, PPV and NPV of 91.67, 40.32, 42.64 and 90.91% respectively whereas at a score of 95 the sensitivity, specificity, PPV and NPV were 43.33, 88.81, 63.41, 77.78% respectively. Area under the receiver operating characteristics curve was 0.736 (95% CI = .661-.811).

CONCLUSION

CAN score is a potential screening tool for frailty among older adults; it is generated automatically and provides acceptable diagnostic accuracy. Hence, the CAN score may be a useful tool to primary care providers for detection of frailty in their patient panels.

摘要

背景

衰弱是一种对压力源脆弱的状态,在老年人中很普遍,与更高的发病率、死亡率和医疗保健利用有关。有多种工具用于测量衰弱;大多数都很耗时。护理评估需求(CAN)评分是使用统计模型从电子健康记录数据中自动生成的。CAN 评分的计算方法符合衰弱的缺陷积累模型。在 95%的百分位,CAN 评分是退伍军人人群住院和死亡的预测指标。本研究的目的是验证 CAN 评分作为初级保健中衰弱的筛查工具。

方法

这是一项横断面验证研究,将 CAN 评分与基于全面老年评估的 40 项衰弱指数参考标准进行比较。我们纳入了来自老年医学门诊的社区居住的 65 岁以上男性患者。我们计算了 CAN 评分的敏感性、特异性、阳性预测值、阴性预测值和诊断准确性。

结果

研究纳入了 184 名 65 岁以上的患者:97.3%为男性,64.2%为白人,80.9%为非西班牙裔。基于 CGA 的衰弱指数将 14.1%定义为健壮,53.3%为虚弱前期,32.6%为虚弱。对于虚弱的患者,统计分析表明,CAN 得分为 55 时,敏感性、特异性、阳性预测值和阴性预测值分别为 91.67%、40.32%、42.64%和 90.91%,而得分为 95 时,敏感性、特异性、阳性预测值和阴性预测值分别为 43.33%、88.81%、63.41%和 77.78%。受试者工作特征曲线下面积为 0.736(95%置信区间=0.661-0.811)。

结论

CAN 评分是老年人衰弱的潜在筛查工具;它是自动生成的,并提供可接受的诊断准确性。因此,CAN 评分可能是初级保健提供者在其患者群体中检测衰弱的有用工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/56fa/5935952/b5e44dca1f38/12877_2018_802_Fig1_HTML.jpg

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