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[医院内药物警戒在药物差错检测中的重要性]

[The importance of intra-hospital pharmacovigilance in the detection of medication errors].

作者信息

Villegas Francisco, Figueroa-Montero David, Barbero-Becerra Varenka, Juárez-Hernández Eva, Uribe Misael, Chávez-Tapia Norberto, González-Chon Octavio

机构信息

Servicio de Farmacovigilancia. Fundación Clínica Médica Sur. Ciudad de México, México.

Unidad de Investigación Traslacional. Fundación Clínica Médica Sur. Ciudad de México, México.

出版信息

Gac Med Mex. 2018;154(2):172-179. doi: 10.24875/GMM.18002549.

Abstract

INTRODUCTION

Hospitalized patients are susceptible to medication errors, which represent between the fourth and the sixth cause of death. The department of intra-hospital pharmacovigilance intervenes in the entire process of medication with the purpose to prevent, repair and assess damages.

OBJECTIVE

To analyze medication errors reported by Mexican Fundación Clínica Médica Sur pharmacovigilance system and their impact on patients.

METHOD

Prospective study carried out from 2012 to 2015, where medication prescriptions given to patients were recorded. Owing to heterogeneity, data were described as absolute numbers in a logarithmic scale.

RESULTS

292 932 prescriptions of 56 368 patients were analyzed, and 8.9% of medication errors were identified. The treating physician was responsible of 83.32% of medication errors, residents of 6.71% and interns of 0.09%. No error caused permanent damage or death.

CONCLUSION

This is the pharmacovigilance study with the largest sample size reported.

摘要

引言

住院患者易发生用药错误,用药错误是导致死亡的第四至第六大原因。医院内药物警戒部门在整个用药过程中进行干预,目的是预防、纠正和评估损害。

目的

分析墨西哥南方临床医疗基金会药物警戒系统报告的用药错误及其对患者的影响。

方法

2012年至2015年进行的前瞻性研究,记录给予患者的用药处方。由于数据具有异质性,以对数尺度的绝对数描述数据。

结果

分析了56368例患者的292932张处方,发现8.9%的用药错误。主治医生对83.32%的用药错误负责,住院医生负责6.71%,实习生负责0.09%。没有错误导致永久性损害或死亡。

结论

这是报告的样本量最大的药物警戒研究。

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