Sugiyama M, Yamane H, Tamuro T, Uekawa M, Morisaki N, Miyamoto K, Nakai Y
Department of Otorhinolaryngology, Osaka Municipal Shirokita Citizen's Hospital, Japan.
Acta Otolaryngol Suppl. 1988;454:138-47. doi: 10.3109/00016488809125017.
Among the four subsets of tonsillar T cells, active cells were most abundant in the helper T subset, followed by the cytotoxic T, inducer T, and suppressor T subsets in order of decreasing cell count. The number of active cells was very small in the suppressor T subset. Plasma cells (PCA-1-positive cells) accounted for only about 3% of tonsillar cells. However, nearly half of the tonsillar B cells were activated (positive for Ba, being either Ba+/IgD+ or Ba+/IgD-). Ba-positive cells were hardly found in the population of peripheral-blood B cells. Ba+/IgD+ cells, which are ready to be transformed to cyclic cells or dormant cells depending upon the degree of stimulation, outnumbered cyclic cells. Many Ba+/IgD+ cells were present even in the small tonsils of adults, although these cells were very scarce in the peripheral blood. These findings show that the tonsil is prepared to perform immunologic functions in prompt response to external stimuli.
在扁桃体T细胞的四个亚群中，辅助性T亚群中的活化细胞最为丰富，其次是细胞毒性T、诱导性T和抑制性T亚群，细胞数量依次递减。抑制性T亚群中的活化细胞数量非常少。浆细胞（PCA - 1阳性细胞）仅占扁桃体细胞的约3%。然而，近一半的扁桃体B细胞被激活（Ba阳性，即Ba+/IgD+或Ba+/IgD-）。在外周血B细胞群体中几乎找不到Ba阳性细胞。Ba+/IgD+细胞可根据刺激程度转化为循环细胞或静止细胞，其数量超过循环细胞。即使在成人的小扁桃体中也存在许多Ba+/IgD+细胞，尽管这些细胞在外周血中非常稀少。这些发现表明，扁桃体准备好在对外界刺激的快速反应中发挥免疫功能。
