Massimino Maura, Biassoni Veronica, Miceli Rosalba, Schiavello Elisabetta, Warmuth-Metz Monika, Modena Piergiorgio, Casanova Michela, Pecori Emilia, Giangaspero Felice, Antonelli Manila, Buttarelli Francesca Romana, Potepan Paolo, Pollo Bianca, Nunziata Raffaele, Spreafico Filippo, Podda Marta, Anichini Andrea, Clerici Carlo Alfredo, Sardi Iacopo, De Cecco Loris, Bode Udo, Bach Ferdinand, Gandola Lorenza
Pediatric Unit, Fondazione IRCCS Istituto Nazionale dei Tumori, (INT), Via Venezian 1, 20133, Milano, Italy.
Medical Statistics, Biometry and Bioinformatics Unit, Fondazione IRCCS Istituto Nazionale dei Tumori (INT), Via Venezian 1, 20133, Milano, Italy.
J Neurooncol. 2018 Jul;138(3):679-680. doi: 10.1007/s11060-018-2893-6.
The therapeutic experience reported in the paper was conceived after the use of nimotuzumab and radiotherapy (BSCPED-05 international multicentric trial, EUDRACT 2005-003100-11) in 2009 when we decided to explore the activity of the same combination plus vinorelbine (see the paper for the rationale).
本文所报道的治疗经验是在2009年使用尼妥珠单抗和放疗(BSCPED - 05国际多中心试验,欧盟临床试验注册号2005 - 003100 - 11)之后构思出来的,当时我们决定探索相同组合加长春瑞滨的活性(有关基本原理见本文)。