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坦桑尼亚莫希脑瘫患儿尿路感染的患病率及抗菌药物敏感性模式

Prevalence and antimicrobial sensitivity pattern of urinary tract infection among children with cerebral palsy, Moshi, Tanzania.

作者信息

Ryakitimbo Amon, Philemon Rune, Mazuguni Festo, Msuya Levina

机构信息

Department of Pediatric and Child Health, Kilimanjaro Christian Medical University College, Moshi, Tanzania.

Department of Pediatric and Child Health, Kilimanjaro Christian Medical Centre, Moshi, Tanzania.

出版信息

Pediatric Health Med Ther. 2018 May 8;9:59-65. doi: 10.2147/PHMT.S159766. eCollection 2018.

DOI:10.2147/PHMT.S159766
PMID:29774893
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5947104/
Abstract

BACKGROUND

Urinary tract infection (UTI) in children with cerebral palsy (CP) is a challenging yet common clinical condition. Children with CP bare the greatest risk of contracting UTI because of their difficulties in neuromotor control which lead to delay of bladder control, causing incomplete bladder emptying and urine retention.

METHOD

This was an analytical cross-sectional study that was conducted from September 2016 to March 2017 at Comprehensive Community Based Rehabilitation in Tanzania - Moshi and Kilimanjaro Christian Medical Centre Neurological Pediatrics Outpatient Clinic. All children who met the inclusion criteria were studied. Urine samples were collected at one point by catheterization, and urine dipstick and urine culture were done. Data were analyzed using SPSS version 20.

RESULTS

A total of 99 children were enrolled in the study. The median age was 4 years (3-8 years); 53.5% were aged between 2 and 4 years. More than half were male. UTI was detected in 13.1% (n=13) of the children. Five causative agents of UTI were isolated, namely , , , , and . The two most common organisms, and , both had low sensitivity to ampicillin and co-trimoxazole while they were sensitive to ciprofloxacin and ceftriaxone.

CONCLUSION

UTI is a common finding among children with CP. and are the commonest causative agents and are sensitive to ciprofloxacin and ceftriaxone but have low sensitivity to ampicillin and co-trimoxazole.

摘要

背景

脑瘫(CP)患儿的尿路感染(UTI)是一种具有挑战性但常见的临床病症。由于脑瘫患儿存在神经运动控制困难,导致膀胱控制延迟,引起膀胱排空不全和尿潴留,因此他们患尿路感染的风险最高。

方法

这是一项分析性横断面研究,于2016年9月至2017年3月在坦桑尼亚莫希的综合社区康复中心和乞力马扎罗基督教医学中心神经儿科门诊进行。对所有符合纳入标准的儿童进行研究。通过导尿一次性采集尿液样本,并进行尿试纸检测和尿培养。使用SPSS 20版软件进行数据分析。

结果

共有99名儿童纳入研究。中位年龄为4岁(3 - 8岁);53.5%的儿童年龄在2至4岁之间。超过一半为男性。13.1%(n = 13)的儿童检测出尿路感染。分离出5种尿路感染病原体,分别为 、 、 、 和 。两种最常见的病原体 和 对氨苄西林和复方新诺明的敏感性较低,而对环丙沙星和头孢曲松敏感。

结论

尿路感染在脑瘫患儿中很常见。 和 是最常见的病原体,对环丙沙星和头孢曲松敏感,但对氨苄西林和复方新诺明敏感性较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee9/5947104/db64caa582ec/phmt-9-059Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee9/5947104/db64caa582ec/phmt-9-059Fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1ee9/5947104/db64caa582ec/phmt-9-059Fig1.jpg

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BMJ. 2016 Mar 15;352:i939. doi: 10.1136/bmj.i939.
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Risk Factors for Recurrent Urinary Tract Infection and Renal Scarring.
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