血卟啉醚——II. 方法改进、二己基醚、二环己基醚和二苯醚的合成及其初步生物学评价
Hematoporphyrin ethers--II. Improvements in method, synthesis of the dihexyl, dicyclohexanyl and diphenyl ethers and their preliminary biological evaluation.
作者信息
Rimington C, Rønnestad A, Western A, Moan J
机构信息
Institute for Cancer Research, Department of Biophysics, Oslo, Norway.
出版信息
Int J Biochem. 1988;20(10):1139-49. doi: 10.1016/0020-711x(88)90260-1.
PMID:2977762
Abstract
- Hematoporphyrin 2.4-dihexyl, -dicyclohexanyl and -diphenyl ethers have been synthesized. 2. Their chemical and physical properties are recorded. The possibility of isomerism is discussed. 3. Preliminary tests have indicated that they possess high photosensitizing efficiency on human cancer cells.
摘要
- 已合成血卟啉2,4 - 二己基醚、2,4 - 二环己基醚和2,4 - 二苯基醚。2. 记录了它们的化学和物理性质。讨论了异构现象的可能性。3. 初步试验表明，它们对人类癌细胞具有高光敏效率。
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