窄谱中波紫外线治疗期间，黑素细胞痣覆盖不透明胶带和防晒霜乳膏后的皮肤镜变化。
Dermoscopic changes in melanocytic nevi covered with both opaque tape and sunscreen cream during narrowband ultraviolet B therapy.
作者信息
Kekeç Derya Ök, Kaçar Nida, Karaarslan Işıl Kılınç
机构信息
Denizli Public Hospital, Denizli, Turkey.
Department of Dermatology, Pamukkale University, Denizli, Turkey.
出版信息
Dermatol Pract Concept. 2018 Apr 30;8(2):132-139. doi: 10.5826/dpc.0802a13. eCollection 2018 Apr.
BACKGROUND
Ultraviolet (UV) light may cause dermoscopic changes on melanocytic nevi (MN).
OBJECTIVES
To investigate the effects of sunscreen cream (SSc) application on dermoscopic changes in MN during narrowband UVB (NBUVB) therapy.
METHODS
Half of the randomly selected MN in each patient were covered with opaque tape and SSc [SSc(+)], and the rest were covered with only opaque tape [SSc(-)] during NBUVB treatment sessions.
RESULTS
More SSc(-) MN displayed dermoscopic changes at end of NBUVB therapy compared to the start of therapy (p=0.035). The number of the MN that decreased in size and showed loss of structure was significantly higher in SSc(-) MN (p=0.04 and p=0.026, respectively).
CONCLUSIONS
Sunscreen in combination with opaque tape may contribute to some dermoscopic changes in melanocytic nevi, including decrease in size and loss of structure.
背景
紫外线（UV）可导致黑素细胞痣（MN）出现皮肤镜变化。
目的
研究在窄谱中波紫外线（NBUVB）治疗期间涂抹防晒霜（SSc）对MN皮肤镜变化的影响。
方法
在NBUVB治疗期间，为每位患者随机选取的一半MN用不透明胶带和SSc覆盖[SSc(+)]，其余的仅用不透明胶带覆盖[SSc(-)]。
结果
与治疗开始时相比，更多的SSc(-) MN在NBUVB治疗结束时出现了皮肤镜变化（p=0.035）。SSc(-) MN中尺寸减小且结构消失的MN数量显著更多（分别为p=0.04和p=0.026）。
结论
防晒霜与不透明胶带联合使用可能会导致黑素细胞痣出现一些皮肤镜变化，包括尺寸减小和结构消失。
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