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[儿童鼻神经鞘瘤伴颅底破坏(1例报告及文献复习)]

[Nasal schwannoma with skull base destruction in a child (a case report and literature review)].

作者信息

Kapitanov D N, Satanin L A, Chernikova N A, Shishkina L V, Shelesko E V, Arustamyan S R, Bukharin E Yu

机构信息

Burdenko Neurosurgical Institute, 4-ya Tverskaya-Yamskaya Str., 16, Moscow, Russia, 125047.

出版信息

Zh Vopr Neirokhir Im N N Burdenko. 2018;82(2):100-106. doi: 10.17116/oftalma2018822100-106.

Abstract

Schwannomas (neurinomas) are benign, encapsulated, and slow-growing neoplasms developing from any peripheral, cranial, or vegetative nerve that has the Schwann sheath. Schwannomas of the nasal cavity and paranasal sinuses in adults occur rarely, less than 4% of cases. The world literature lacks similar data for the pediatric age group because these tumors in children are unique and extremely rare. The most common clinical symptoms of sinonasal schwannoma are nasal breathing disorders, hyposmia or anosmia, and snoring at night. Other symptoms are associated with intranasal schwannoma invasion of neighboring organs and tissues and include exophthalmos, epiphora (lacrimation), headaches, and anesthesia in the facial area. In this article, we describe a rare case of diagnosis and successful surgical treatment of a child with intranasal schwannoma destructing the skull base.

摘要

施万细胞瘤(神经鞘瘤)是一种良性、有包膜且生长缓慢的肿瘤,由任何具有施万鞘的周围神经、颅神经或自主神经发展而来。成人鼻腔和鼻窦的施万细胞瘤很少见,不到病例的4%。世界文献中缺乏小儿年龄组的类似数据,因为儿童中的这些肿瘤很独特且极其罕见。鼻窦施万细胞瘤最常见的临床症状是鼻呼吸障碍、嗅觉减退或嗅觉丧失以及夜间打鼾。其他症状与鼻内施万细胞瘤侵犯邻近器官和组织有关,包括眼球突出、溢泪(流泪)、头痛以及面部区域麻木。在本文中,我们描述了一例罕见的诊断病例及成功手术治疗破坏颅底的儿童鼻内施万细胞瘤的案例。

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